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FREELEX is preferred Aptamer Selection Process

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preet gambhir
FREELEX is preferred Aptamer Selection Process

Aptamers are used in different therapeutics and diagnostic applications. Chemical modification processes are employed to increase the nuclear resistance that is offered by aptamers which aids in enhancing the aptamer’s therapeutic properties. This generates plethora of opportunities for the market players in the global aptamer market. Research institutions contribute in increasing the demand for aptamers and products associated with it. Research and development activities have introduced new aptamer-based drugs and drug-carriers. Newly introduced drugs are applied to discover new diagnostic tools and generate lucrative opportunities for the manufacturers in the global market.

Presence of major players influence market in Asia Pacific

The latest Fact.MR report predicts the global aptamer market to grow at 21% CAGR during the forecast period 2020-2025. North America is the most prominent region in the global aptamer market owing to the advanced technologies offered by early-bird. The therapeutics and diagnostics equipment market experiences continuous R&D activities which are performed to suffice the growing demand for aptamers, thereby propelling the global aptamer market. Diagnostic tools are highly demanded in Europe on the backdrop of surge in awareness regarding different health issues that arise from infectious and chronic diseases. Biotechnology industry is known to generate huge opportunities in aptamer market in Europe.

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Fact.MR report projects Asia Pacific aptamer market to be heavily influenced by presence of major market players in the region. Aptamer market in regions like Europe, North America and Asia Pacific is positively influenced by technological knowledge sharing and pharmaceutical knowledge enhancements which is brought in by the market players in the region to expand their market presence.

Restricted knowledge about aptamer is a challenge

Selection technique for aptamer is a significant determinant in determining the growth trajectory of global aptamer market. Major stake holder SOMALOGIC, INC. launched SOMAmer as selection platform for next generation which will extract quality aptamers for different applications. SELEX technique is the most sought after technique for aptamer selection. It is estimated to own 80% of the global aptamer market owing to its potential to identify protein binding site on RNA. Several organizations are investing in R&D activities to discover aptamer selection processes that are cost-effective along with being time-efficient. FRELEX and Magnetic-assisted Rapid Aptamer Selection are expected to exhibit high adoption rate in the forecast period because of their simple enzymatic steps that fasten the selection process.

Lack of quality and safety standards in aptamer processes is a restraining factor for the market growth. Developed nations have strict approval process for technologies and processes associated with aptamer. Aptamer market in Europe especially suffers from tedious documentation process for clinical trials and oligonucleotide guidelines to verify the quality requirements in general. Many regions like Middle East and Africa exhibit slow aptamer market growth owing to low awareness about molecules like aptamers. Many aptamer characteristics are unexplored, posing challenge to manufacturers in technological front. Aptamer’s low molecular weight degrades the biological media very rapidly. This unwanted characteristic demands proper synthesis for the negative impact to stay subsided. Moreover, short life of aptamer is also a market growth inhibiting factor that poses hurdles in practical implementation of aptamers.

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