Nexium 20mg may be too familiar to people with gastroesophageal reflux disease, or stomach ulcers ... But how to use the medicine is right not everyone knows. The following article will be the sharing of drug lookup on Nexium medicine. Hopefully, through the content of the article, you will better understand the medicine.
What is Nexium 20mg?
Nexium 20mg contains a medicine called esomeprazole. This drug belongs to a group of drugs called proton pump inhibitors. They work by reducing the amount of acid your stomach makes.
Drug composition of Nexium 20mg
Generic name: magnesium esomeprazole (oral)
Brand name: Nexium
Nexium, marketed as Violet, is one of the most widely prescribed medications in the United States.
Esomeprazole, generic name of Nexium, is chemically similar to omeprazole, the active ingredient in Prilosec. AstraZeneca produces prescription versions of both Nexium and Prilosec. Prevacid and Protonix are two other related drugs.
The pharmacology of Nexium 20mg
Contains 20mg of esomeprazole.
A oblong shape and light pink.
One side is engraved 20mg.
The other side is engraved with "A" above and "EH" below.
Glycerol monostearate 40-55.
Close OXid (20mg tablet: red brown iron oxide, 20mg tablet: Yellow iron OXid) (E 172)
Methacrylic acid ethyl acrylate copolymer (1: 1) 30% dispersant.
Synthetic paraffin, macrogol 6000.
Sodium Stearyl fumarate.
Sugar spheres (sucrose and corn starch).
Talc, titanium dioxide (E 171).
Drug toxicity Nexium 20mg
A 2017 study looked at 125,000 PPI users for five years. Half of those with chronic kidney damage never had kidney problems before taking PPIs. A 2016 study found that long-term PPI use nearly doubles the likelihood of a patient's kidney failure.
In 2016, researchers linked the use of PPI with a 21% increased risk of stroke. They presented their findings at the American Heart Association Scientific Session 2016.
A 2017 study found that PPIs can double the risk of stomach cancer in some patients. Researchers found an increased risk in people infected with the previous Helicobacter pylori. They have published their results in the journal BMJ Gut.
A 2018 study found that PPIs taken to prevent esophageal cancer could actually cause it. Researchers in Sweden found that PPI could be responsible for five percent of all cases there. They have published their results in Cancer Epidemiology.
Drug interaction Nexium 20mg
Drug interactions can change the way your medications work or increase your risk of serious side effects.
Keep a list of all products you use (including prescription / over-the-counter medicines and herbal products) and share them with your doctor and pharmacist. Do not start, stop or change the dosage of any medicine without your doctor's approval.
Some products that may interact with this drug include: cilostazol, clopidogrel, methotrexate (especially in high doses), rifampin, St John's wort.
Some products need stomach acids so that the body can absorb them properly. Esomeprazole reduces stomach acid, so it can change the effectiveness of these products.
Some of the affected products include atazanavir, erlotinib, nelfinavir, pazopanib, rilpivirine, some azole antifungals (itraconazole, ketoconazole, posaconazole), among others.
Esomeprazole is very similar to omeprazole. Do not use any medicine that contains omeprazole while using esomeprazole.
This medicine may interfere with some laboratory tests, which may cause false test results. Make sure laboratory staff and all your doctors know you use this medicine.
*** Note: Information about Nexium 20mg drug for the purpose of sharing knowledge for reference only, patients are not allowed to arbitrarily use the drug, all information on drug use must follow the appointment of a specialized physician subjects.
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