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Risk factors include systemic inflammatory response and sepsis [3, 4], several medications [5], prolonged immobility and bed rest [5], and severity of organ dysfunction [6].
Apart from controlling for potentially reversible risk factors and subsequent adjustment of therapy, no other effective means have been suggested so far for the prevention of ICU-AW.
We have previously shown that EMS in ICU patients induces a systemic acute effect on the microcirculation of muscles not applied [15] and preserves the mass of muscle groups applied [16].
We have also found that EMS prevents ICU-AW, which was diagnosed in 12.5% of the EMS group in comparison to 39.3% of the control group and results in shorter duration of weaning from mechanical ventilation [17].
Secondary aims were to establish the relationship between different tests of muscle strength evaluation and to explore the technical issues in relation to muscle strength assessment in the ICU setting.
Exclusion criteria were age under 18, pregnancy, obesity (BMI > 35 kg/m2), preexisting neuromuscular disease (e.g., myasthenia gravis, Guillain-Barré), diseases with systemic vascular involvement such as lupus erythematosus, technical restrictions that did not allow the implementation of EMS such as bone fractures or skin lesions (e.g., burns), and end-stage malignancy.
Amazingly, there are now companies that are based around the development of novel psychedelics for mental health applications.
Recently, I spoke with Ian McDonald, Founder of Bright Minds Biosciences, a group of veteran drug hunters that are looking to change the template for the treatment of depression.
Wipro's enterprise application services, working at intersection of cloud, mobility, analytics offer smart applications, SAP to generate effective, future-ready enterprise solutions
