New scientific research points to resveratrol as a tool to help repair damaged heart tissue after a heart attack.
Dipak Das, co-author and research professor at the University of Connecticut’s Cardiovascular Research Center, was recently cited in the Journal of Molecular Medicine in an exciting new find on Resveratrol.
The researchers mimicked the effects of a heart attack by essentially puncturing the hearts of mice, then stitching them up. Stem cells were then directly injected into the animals’ hearts in an attempt to determine if the cells would regenerate heart tissue and heal the wound.
As a result, resveratrol appeared to provide favorable conditions for the wounds to heal. Paired with the stem cells, “cardiac function was significantly improved,” the text said.
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The stem cells survived working alone on the wounds for a period of seven days, whereas with the aid of resveratrol, they continued to thrive for a period of 28 days.
the study maintained. While more study is still needed, there is hope that heart attach survivors could enjoy the benefits of resveratrol treatments in the future.
According to a new study conducted by Jill Crandall, human patients suffering from impaired glucose tolerance (IGT) - also known as “pre-diabetes.”
Resveratrol is an organic polyphenolic compound found in red wine, grapes, and other foods that have a number of antioxidants, anti-inflammatory, and cardioprotective health benefits. The results of the study were presented during a meeting of the American Diabetes Association.
Insulin Resistance
A related study by Meredith Hawkins, M.D., from the Global Diabetes Initiative at Einstein reported on the effect of resveratrol in overweight, middle-aged subjects who were insulin resistant. As people either age or gain weight, they don’t respond to insulin as well as younger or thinner people do.
Some people even reject the action of insulin- a condition known as insulin resistance- and as a result don’t burn or take in glucose competently, which can eventually result in diabetes.
In her resveratrol study, Dr. Hawkins detected a 40 percent increase in insulin sensitivity, as well as improvements in mitochondrial function, concluding that resveratrol supplementation may serve as a treatment for this condition.
Resveratrol Dosage Used
Resveratrol supplements containing resveratrol quantities much higher than found in foods or wine- were given to people in this study. According to Dr. Crandall, the concentrations of Resveratrol contained in the supplements were much higher than “even several bottles of wine”.
Buccal Delivery is Key to Resveratrol Absorption and Bio-Availability
The only way to safely consume dosages of resveratrol similar to those used in clinical studies is through supplementation.
Studies show that the most efficient way of consuming resveratrol supplements is by directly absorbing the substance through the inside of the mouth without swallowing. This method is known as “buccal delivery.”
When absorbed through the mouth’s epithelial tissue, resveratrol supplements avoid being directly metabolized by the intestines and liver. In human experiments, only trace amounts of resveratrol were found in plasma when taken as pills or capsules.
On the other hand, buccal delivery supplementation with intraoral absorption produced up to 250 times higher levels of unchanged resveratrol in blood plasma. Resveratrol fast melting tablets from EZ MELTS are designed for buccal delivery, and provide the highest dosage of resveratrol available in an intraoral supplement in the market.
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