Method of Maternal Lineage DNA Testing The common applications of a Maternal Lineage Ancestry DNA Test include: Genealogical Studies Medical Researches for Genetic Predisposition to certain diseases In Drug development studies on certain populations Tracing down the missing mother who gave up her child in an adoption A child always inherits half of its DNA from the father and the other half from the mother, making genetic relatioThe DNA holds a vast set of genetic information that serves as the basis of various genetic tests for a number of applications. Applications of a Maternal Lineage DNA Test nship identification possible between a child and the biological parents. While a male child inherits the Y chromosome from the father, both male and female children inherit mt DNA from the mother unchanged. Human mitochondrial DNA is 16,569 base pairs long, which is much shorter than the human genome DNA. The first step in mtDNA analysis for maternal lineage is to isolate the DNA from the epithelial cells collected on the buccal swabs, followed by PCR (Polymerase Chain Reaction), and finally sequencing. Following this step HVR1, HVR2 coding regions are analyzed and matched against the existing database to give the mtDNA haplogroup data.