Laurence Lafarge

Laurence Lafarge

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Following 45
US
PHOENIX, Ariz. -- Nov. 14, 2019 -- Following a nearly 25-year search across three continents, parents of a pair of sisters -- who as children slowly became paralyzed from the waist down -- finally have a diagnosis, according to researchers at University of Southern California (USC) and Translational Genomics Research Institute (TGen), an affiliate of City of Hope.These findings were reported today in the scientific journal Human Mutation.Thanks to a chance viewing on French TV of a story about another physically disabled child who regained her mobility after being diagnosed at TGen's Center for Rare Childhood Disorders (the Center), the parents of the two sisters contacted TGen, hoping to end their decades-long diagnostic odyssey."The girls' parents were one of the many who emailed me after seeing the TGen interview on French TV," recalled Dr. Matt Huentelman, Professor of TGen's Neurogenomics Division, Scientific Director of the Center, and one of the paper's authors.The sisters have required multiple foot surgeries associated with their condition, have no bladder or bowel control, and require daily assistance with bathing, feeding and dressing.In 2014, the parents saw a story featured on France 2, the French national television channel, about a young girl who after being diagnosed and treated at the Center, was able to discard her wheelchair, stand and walk -- and even dance.
UK
This year the global Xbox celebration is taking place in the Copper Box Arena, London with Microsoft promising the event will be "filled with news, first looks and surprises, and Xbox FanFest, all livestreamed and starting on Inside Xbox".Last year's event saw Microsoft announce the big news that Obsidian Entertainment and inXile Entertainment had joined Microsoft Studios, alongside Xbox Game Pass updates, some Black Friday deals news and a bunch of new Xbox One game reveals.However, with Xbox Project Scarlett due for release in late 2020, we're expecting X019 to be a much bigger show – we may even get a closer look at Microsoft's next-generation hardware.TechRadar will be reporting live from X019 in London, bringing you the biggest announcements as they happen.Marketed as "the annual global celebration of all things Xbox", the event is typically Microsoft's way of updating fans on the things it announced at E3 as well as making big new announcements or providing first looks at upcoming games and/or hardware.With Xbox Project Scarlett releasing in late 2020, we think (and hope) X019 will be dominated by news on Microsoft's next-generation console.
US
Luckily, there are more than a few midrange phones to choose from that have managed to pack high-end features into an affordable handset.The Moto G7 is perfect for those fans of a massive screen.With a pixel resolution of 2,270 x 1,080 along with a 19:9 aspect ratio, you’re most likely set for a comfortable viewing experience.It runs on Android 9.0 Pie and comes with quirky Moto Actions that allow you to create custom shortcuts as well as utilize its display options.Flip it over and you’ll find the 12-megapixel main camera which is complemented by the secondary 5-megapixel camera for depth.You’ll be able to take a good shot granting there is enough light.
US
You’d pick a Civ and try to push toward a one of half-a-dozen victory conditions, instead of adaptingThis isn’t inherently a bad concept, but it is a relatively niche one, and now Civ is no longer the dominant force in strategy games.Paradox Interactive games like Europa Universalis 4 have moved in, with a focused simulation of a specific historical era and no rigid endgame.Total War, Civ’s only real long-term competitor for the greatest strategy series, has had an uneven but largely fruitful decade.This might sound limited, but there’s actually a lot of room in the anti-Civ genre — despite Civilization’s monumental place in the strategy game universe, it’s only inspired a handful of direct competitors of turn-based games covering the entirety of history.It is an attempt to make a game about all of human history that’s about making the most about the position players are in at any given time — about reacting and adapting instead of merely executing.
China
Chinese consumers collectively spent 268.4 billion yuan (US$38.4 billion) for Alibaba’s Singles’ Day, setting a new record for the 24-hour shopping extravaganza.The final tally for this year’s Singles’ Day was up nearly 26% compared to last year’s figure of 213.5 billion yuan (US$30.5 billion), as consumption during the festival remained robust despite a protracted US-China trade war – now in its 17th month – and a slowdown in the Chinese economy.Alibaba’s Singles’ Day shopping festival, which falls on November 11 every year, is the world’s largest of its kind, where shoppers scoop up everything from consumer electronics to luxury items and even cars.“Singles’ Day is becoming more recognized worldwide […] but since it is still very much a domestic holiday and event, it is a true test of Chinese consumer power,” said Benson Ng, EY Greater China digital advisory leader.While the company’s ecommerce marketplaces Tmall and Taobao are traditionally the mainstays of the annual shopping extravaganza, this year’s festival includes business-to-business ecommerce platforms like AliExpress as well as Lazada, Alibaba’s Southeast Asian ecommerce subsidiary, as the company taps international consumers.Gross merchandise value (GMV) for the Double 11 Global Shopping Festival is the total value of orders settled through Alipay on Alibaba’s consumer-facing core commerce platforms, as well as Lazada and AliExpress, within a 24-hour period on November 11.
China
The Redmi Note 8 Pro is already selling globally but the company now has a new colour option.In addition to the ice jade, pearl white, and electro-optic ash, Redmi has now added a “dark blue” colour in Taiwan.This smartphone is currently on “Arrival Notice” but it will be available from November 11.The price of 6GB+64GB is NT$6,599 ($218) while the 6GB+128GB version costs NT$7,599 ($251).The Redmi Note 8 Pro comes with an Helio G90T processor that uses 2 ARMCortex-A76 and 6 Cortex-A55 cores.On the screen side, this smartphone features a 3D four-curved glass body with a 6.53-inch screen and a resolution of 2340×1080.
Sweden
the two Companies have moved out of their marketing site to social media sites,” said Anna Hult, who is a lawyer for the agency.When introduced in the in the consumer credit act of self-restraint must be exercised when one is doing commercials for the loans.the Criticism has among other things been directed towards the betalbolaget Clear that the existence of hip-hop star Snoop Dogg to market the mortgages and to the låneappen Bynk in the commercial, the protagonist would like to take out a loan to travel to London to watch football.They put the marketing in the hands of the influencers.the Agency has set down his foot against a number of intermediaries, thus, the companies that collect the credit from the other players without having to give out your own.as An example, is Anyfin, which is called the competition of the ”lånehajar” but, in fact, was forced to withdraw its promotional campaign as it is purported to embellish the level of indebtedness.
UK
Boeing aced the crew escape test of its Starliner spacecraft this morning, with the pod earmarked to eventually take astronauts to the International Space Station and beyond demonstrating NASA’s vital safety system.The test is designed to simulate a launch pad emergency, shifting the Starliner away from the Atlas V launch rocket to keep the human occupants inside safe.Clearly that’s not something NASA or anybody else wants to have to test out for real, but it’s an important consideration nonetheless.Considering an Atlas V carries more than a million pounds of propellant across its various stages, that’s not something an astronaut would want to be nearby should a problem occur.The CST-100 Starliner spacecraft lifts off – in an unscrewed state – from a test stand, in this case at the U.S. Army’s White Sands Missile Range in New Mexico.By firing its launch abort engines, of which there are four, along with several of its orbital maneuvering and attitude control thrusters, it mustered 190,000 pounds of thrust.
US
Google tapped into the expertise of wedding photographers in the process of building the Pixel 4‘s face retouching feature, according to the Pixel camera’s lead product manager, Isaac Reynolds.Reynolds, in an interview with The Vergecast, said that his team brought in wedding photographers to help them with not crossing certain lines, such as “making faces thinner, lips larger, and noses smaller,” while still making sure that people looked better after activating the feature.Reynolds’ team asked the photographers what they did to retouch the photos of their clients since people at weddings already put in effort to look their best on that day.The Pixel 4 face retouching feature tries to emulate what the wedding photographers do, though one thing that Reynolds specifically mentioned in the interview is skin smoothing.With skin-smoothing, the Pixel 4 face retouching feature attempts to remove “what you look like today that isn’t you,” Reynolds said.One example is the red mark left behind when people rest their faces on their hands for too long — the camera will try to remove that mark while increasing exposure to create a “glow.”
UK
The vulture is often depicted as death’s maligned servant, circling ominously in the clouds in search of decay.Also, our New World vultures shit and piss all over their legs to keep cool.The patron goddess of upper Egypt, Nekhbet, was a represented as a white vulture.Recent research has found that New World turkey and black vultures have incredibly low levels of bacterial diversity in their stomachs, 76 kinds versus 562 kinds on their faces.Common vulture gut bacteria include clostridia and fusobacteria – microbes that are harmful to other animals, which the vulture has presumably removed from the environment through their carrion consumption.But our positive associations with vultures likely came to an end during industrialisation.
US
State-owned telecoms operators in China will switch on their 5G networks for the first time on Friday as Beijing aims to catch up with the US.China Unicom, China Mobile, and China Telecom will launch 5G services on Friday with prices starting from 128 yuan per month, equivalent to approximately $18/month.Beijing initially planned to launch 5G services early next year but have accelerated their plans amid increased trade tensions with the US.As of Friday, China will have the largest commercially-operating 5G network in the world.The latest generation network will improve speeds and reliability for consumers while allowing businesses to pursue new use cases such as driverless cars.Chris Lane, and other analysts at Sanford C. Bernstein, wrote in a note to clients on Wednesday:
China
When launching a food and beverage (F) business, most people think it’s all about entertaining new customers, concocting new dishes, and creating enchanting experiences.In Singapore, many restaurant owners are struggling with tighter manpower policies, rising rental prices, and complex supply chains.F businesses also have to find affordable suppliers, keep up with inventory, and manage numerous payments per month.Established in 2017 by Jerry Lim, Steven Seet, Neeraj Sundarajoo, and Keith Tan, the startup wants to enable “horeca” – or hotel, restaurant, and catering – businesses to better manage the procurement of food ingredients.While searching for new opportunities after their 2016 departure from Wunderman, Tan and Sundarajoo came to learn about the high closure rates among restaurants.Together with food service industry veterans Lim and Seet, Zeemart’s founders studied the supply chain to understand how each process – from sourcing to procuring to fulfilling – worked.
US
WhatsApp is finally rolling out fingerprint unlocking to Android phones, some 10 months after the feature was first teased in an early Android beta build.It’s worth noting that WhatsApp has already introduced biometric security to its iPhone app, having added support for Face ID and Touch ID back in February.Touch ID, which involves using your fingerprint to authenticate an app, is available on the iPhone 5S to the iPhone 8 / 8 Plus, after which Apple replaced Touch ID with its facial recognition system.So while we already knew WhatsApp was adding biometric unlocking, today’s announcement finally brings it to the masses.This is a notable development for WhatsApp, given that one of its core selling points is the security it offers through end-to-end encryption.Fingerprint unlocking makes things even more secure as it encourages users to lock the app down even if the device itself is unlocked.
US
On this episode of Digital Trends Live, hosts Greg Nibler and Chris DeGraw discuss the top stories trending in tech, including Apple’s AirPods Pro, Google’s bid for Fitbit, Uber Money, team-building robots, smiling pets, and more.We then go to DT Editor-in-Chief Jeremy Kaplan in New York, who speaks with Devon Greco, founder and chief executive officer of Narbis, about how the company has created eyewear that uses a NASA algorithm to encourage focus and concentration.John Velasco also joins us from DT’s New York studios to take a look at what’s new in smart home tech, including smart lock reviews, automatic curtains, and a bathroom assistant.Nibler then speaks with Dan May, director of Painting Practice, Ltd., who worked on the new HBO series His Dark Materials, about how the company used real-time effects rendering in VR to push filmmaking boundaries.Finally, we go back to Kaplan, who sits down with Chase Watterson, marketing director at iFit, a patented technology that enables two-way interactivity between NordicTrack, ProForm, and FreeMotion exercise equipment and its users.
UK
James Starkie thrown out of Strangers after expletive-laden rant as Tories put law and order at the heart of general election campaign.HuffPost is part of Verizon Media.Verizon Media and our partners need your consent to access your device and use your data (including location) to understand your interests, and provide and measure personalised ads.Verizon Media will also provide you with personalised ads on partner products.Select 'OK' to continue and allow Verizon Media and our partners to use your data, or select 'Manage options' to view your choices.
US
The developer behind SliceCharge and SliceCharge Pro is preparing to offer what it claims is the world’s first mechanical keyboard designed for MacBooks, the NuType.It “locks” into place using notches on the bottom that fit between and around the laptop’s keys.This mechanical keyboard seemingly targets users on the go.In the home or office, many MacBook owners may use traditional, full-sized external keyboards rather than the built-in keyboard.We want to make the mechanical keyboard much smaller and can also use on your mobile devices.This is the origin of NuType.”
UK
Last year, Microsoft began offering a financing program called Xbox All Access.With it, those who sign up can finance the purchase of an Xbox, along with subscriptions to Xbox Live Gold and Game Pass, through monthly payments.Microsoft is bringing back Xbox All Access here at the tail-end of 2019, though this time it has some additions.For starters, the program is now available in the UK and Australia, and like previous iterations of Xbox All Access, you can still use the program to finance an Xbox console and pay it off over 24 months.However, after you’ve made a certain number of payments, you’ll be able to trade in your console and upgrade to Project Scarlett (assuming that is has indeed launched by the time your upgrade rolls around).If you buy an Xbox One X through the program, you can make that upgrade after 12 months, while buying an Xbox One S or Xbox One S All-Digital Edition – the latter of which is new to the lineup this year – makes the upgrade available after 18 months.
UK
While Microsoft has revealed some specs for its dual-screen Surface Duo, one thing that it has remained quiet about until now is the camera.In fact, the prototype it showed off doesn’t even have a rear camera, but that’s something the company is actively working on, and the result will apparently be “world-class”.That claim came from Panos Panay, chief product officer of the Microsoft Devices group, who in an event attended by WindowsArea apparently said “of course we’re working on a world-class camera” for the Surface Duo.He didn’t go into any detail, so we don’t know what will make this camera world-class, but a patent might provide some clues.Microsoft is also working on the Surface NeoCheck out the best smartphones you can buy right now
UK
A former top lawyer at Apple, who was responsible for ensuring that employees weren’t involved in insider trading, has been indicted on charges of insider trading, reports a press release from the U.S. attorney for the District of New Jersey.According to the indictment, the former director of corporate law at Apple, Gene Levoff, allegedly participated in a scheme from 2011 to 2016 in which he defrauded Apple by using insider company financial information to make stock trades.The indictment alleges Levoff sold stock when he learned that Apple posted “lower-than-anticipated revenue and net profit” evading major losses, and it alleges that he traded during a “blackout period” when high-level employees were supposed to be barred from trading.“This scheme to defraud Company-1 and its shareholders allowed Levoff to realise profits of approximately $227,000 [£176,970] on certain trades and to avoid losses of approximately $377,000 [£293,911] on others,” the release states.Apple did not immediately respond to a Gizmodo request for comment.As CNBC points out, the U.S. Securities and Exchange Commission charged Levoff in a civil case in February.
US
Aside from Microsoft coming up with a fix for its Windows 10 bug, this powerful 2-in-1 also received big price cuts across different online stores.Jump on these Surface Book deals to save hundreds off bucks on a top-of-the-class detachable laptop.13.5-inch Microsoft Surface Book 2 dealsWhen we reviewed the Microsoft Surface Book 2, we found that this hybrid manages to go real fast and last forever.This 13.5-inch detachable notebook is an excellent option if you are looking for a compact 2-in-1 that can keep up with your grind.Its display is packed with powerful components, making it a usable tablet by itself.
UK
The Outer Worlds is one of the most anticipated games of 2019, and for good reason.With the Fallout: New Vegas developer at the helm of this massive sci-fi RPG, and a good sense of wacky humor underpinning the action, it looks to put some fun back into a genre weighed down with gray, unrelenting post-apocalyptic landscapes.Enjoying The Outer World's popping colors and lively environments, though, may be a bit harder on some consoles than others.Obsidian has confirmed that The Outer Worlds will only be available to play in 4K resolution on the Xbox One X console – as well as PC – without the same 'enhanced' 4K feature on the PS4 Pro.Regardless of the quality you'll be playing in, The Outer Worlds will launch on PS4, Xbox One, and PC on October 25 – though PC gamers will need to use the Epic Games Store for now.We don't know if Microsoft's acquisition of Obsidian has anything to do with this news, though it sets a sad precedent for developers offering a tiered experience between platforms at the expense of the player experience.
China
The Taiwan government announced that it would investigate Chinese artificial intelligence (AI) and biometrics company Megvii after it was blacklisted by the US government last week, Focus Taiwan reported.Why it matters: The investigation could put at risk Megvii’s recent contract to install a biometric security system at Taiwan’s Taichung Power Plant, with legislators wondering whether the firm’s technology raises national security concerns.It could also complicate Megvii’s plans for its initial public offering (IPO), which, according to co-founder and CEO Yin Qi, it planned to “firmly carry on” with despite “some disturbance” after being blacklisted along with 27 other Chinese government agencies and companies.Yin also said the company has been preparing for possible supply shortages since May in anticipation of being blacklisted and barred from purchasing crucial x86 servers and GPUs subject to US export regulations.Details: In response to the Economic Committee’s concerns, Minister Sheng Jong-chin said he would ask the Ministry of Economic Affairs (MOEA)’s State-Owned Enterprise Commission to launch a comprehensive investigation of the blacklisted companies and instruct the ministry’s Information Management Center to conduct a review.Megvii won a bid to install the security system at Taichung Power Plant on Sept. 12, less than a month before being added to the US government’s blacklist.
US
All eyes are on Netflix this week as the company prepares to report earnings for the third quarter on Wednesday.The streaming giant missed forecasts for subscriber growth during the second quarter, and its stock has taken a beating since.Investors will look for Netflix to add at least 7 million subscribers, address competition from Disney Plus and Apple TV Plus head on, and continue boosting its average revenue per user as overall growth slows.Visit Business Insider's homepage for more stories.Netflix's next earnings report on Oct. 16 will be pivotal for investors evaluating whether Netflix's subscriber woes are a blip or symptom of a more worrisome trend.The third quarter was Netflix's last full period before streaming newcomers Apple TV Plus and Disney Plus launch in November, to be followed by HBO Max and Peacock early next year.
UK
Microsoft has officially announced the general availability of a new Tamper Protection feature for its Windows Defender Antivirus service.The security feature is essentially meant to thwart any attempts made by cybercriminals to break the real-time anti-malware defenses incorporated in Windows.In other words, tamper protection safeguards against “malicious and unauthorized changes to security features, ensuring that endpoint security doesn’t go down.”The setting, which will be on by default for home users, can be accessed as follows:In the search box on Taskbar, type Windows Security and select the optionSelect Virus & threat protection
US
Arcade1Up's remake of the classic arcade machine lets fans relive the four-player fun with a build-it-yourself home version, now on sale at Walmart for $400.After building and playing it, I can tell you as a Turtles fan, this machine was exactly what I hoped it would be -- and the materials are a nice upgrade in quality from last year's Arcade1Up cabinets.Sega Genesis is back with a mini console.There are Pac-Man and Street Fighter II tables, and customers can choose models with classic artwork or a more refined all-black theme.This time around it also includes a riser with custom artwork (the risers were usually sold separately last year) to bring it to standing height.As for the cramped playing space, it wasn't a deal-breaker for me since I was playing with friends and colleagues (that, and it helps that the game doesn't last that long).
China
US game developer Blizzard Entertainment removed a professional gamer from a “Grandmasters” competition for the video game Hearthstone on Tuesday after he made a statement supporting the ongoing pro-democracy protests in Hong Kong, CNET reported.Why it matters: Blizzard’s action sends a message that the company is serious about enforcing its tournament guidelines, which prohibit participants from engaging in any act that brings them “into public dispute, offends a portion or group of the public, or otherwise damages” the California-based company’s image.The move highlights the complex politics that non-Chinese companies must navigate when operating in the country.Details: During an interview on the official Taiwanese Hearthstone stream, Chung “Blitzchung” Ng Wai shouted “Liberate Hong Kong, revolution of our age!” in Mandarin while wearing a gas mask.Blizzard also cancelled Blitzchung’s prize money and banned him from Hearthstone competitions for 12 months.In an interview with Polygon before his ban, Blitzchung acknowledged the divisiveness of his comment, stating that “There will be definitely be negative consequences.”
UK
Even though many businesses in the Gulf region are interested in digitization, only a few of them have moved aggressively while many companies are testing the waters and wondering how to move from strategy to action.Culture is an essential factor in attracting, developing and retaining digital talent," Abdulkader Lamaa, Associate Partner at McKinsey & Company, told TechRadar Middle East.The Gulf has a digital skills gap in experienced software engineers, customer-experience designers, digital marketeers, and data scientists.The limited number of individuals with these skills are looking to be part of a culture that many Gulf companies can’t yet offer.Not enough development arms in regionWhen it comes to local talent, Lamaa said that the region has a large pool of young motivated people graduating every year in relevant domains.
US
Ever heard of the Hall voltage?Discovered by Edward Hall in 1879, it’s the voltage perpendicular to the flow of a conductor’s charge that’s used to measure the deflection of movement caused by a magnetic field.Critically, it communicates information about the charge carriers in a semiconductor, including the presence of negative electrons and positive quasi-particles (called “holes”) and those particles’ speed in an electric field (as well as their density).Over a century after the Hall effect was discovered, researchers from KAIST (Korea Advanced Institute of Science and Technology), KRICT (Korea Research Institute of Chemical Technology), Duke University, and IBM claim to have discovered a technique enabling the extraction of even more information from carriers.A paper published this week in the journal Nature describes how the technique could be used to extract carrier lifetimes, diffusion lengths, and metrics regarding recombination (the process by which electrons and holes annihilate each other).Several studies following the Hall effect’s discovery sought to examine the extent to which the measurement could be performed with photons.
Sweden
Samsung hävdar att det går att vika ihop Galaxy Fold 200 000 gånger.Techsajten Cnet bestämde sig för att kolla om det verkligen stämmer.Samsungs vikbara mobil Galaxy Fold har till sist börjat säljas, och kommer inom några veckor också att lanseras i Sverige.Men hur stryktålig är den nya, härdade designen?Samsung hävdar att mobilen ska gå att vika ihop och vika isär 200 000 gånger inom gångjärnen eller skärmen börjar ge med sig.Cnet fick hjälp av företaget Squaretrade som har byggt en liten robot som kan vika ihop och öppna telefonen i rask takt.
US
Microsoft is adding to its Surface lineup of PCs a device with dual 9-inch displays called the Surface Neo, briefly shown at the company's annual Surface launch event in New York on Wednesday.More conventional new products included the Surface Laptop 3, Surface Pro X and Surface Pro 7 tablets, Surface Earbuds and the SQ1 custom Arm chip.Attached with 360-degree hinges, the displays have more than 60 microcoaxial cables running between the hinges, each thinner than a human hair, Panay said."It's a new expression of Windows 10 that we've been designing and building for the last couple of years, with hundreds of engineers and designers at Microsoft," said Carmen Zlateff, Microsoft Program Manager for Experiences and Devices.During the Surface Neo demonstration, Zlateff showed how the twin displays can be used with multiple apps open and how they can be quickly reorganized depending on what position the device is in and what needs to be visible.For when you feel the need for a full keyboard, Microsoft will offer one that magnetically attaches to one of the displays.
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