As you may have read in our earlier blog, feeling unusually low in mood or depressed is common following critical illness or injury.We often meet patients who are feeling uncharacteristically low or depressed, particularly following a hospital admission.
Given the difficulty patients often encounter in accessing high quality psychological treatments, they may consider trialling anti-depressant medication as an alternative.
For mild-moderate depression psychological treatments are advised (NICE, 2009).
National Guidelines (which provide treatment recommendations in the UK) recommend that anti-depressant medication is only prescribed for patients experiencing moderate-severe depression, alongside a psychological treatment.Furthermore, evidence suggests that anti-depressant medication may not be as effective as first thought.
A recent article in the British Medical Journal (BMJ) has been published by Jakobsen et al.
A placebo effect occurs when an improvement is produced by a placebo treatment, which cannot be attributed to the placebo itself and therefore must be due to the patient’s belief in that treatment.In this review paper, Professor Kirsch and colleagues found that anti-depressant medication had a statistically significant benefit when compared with placebo, but not a clinically meaningful benefit.