Richard Lucarelli

Richard Lucarelli

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UK
Welcome to SHIFT Basics, a collection of tips, explainers, guides, and advice to keep you up to speed with mobility tech. In the early days of motoring, cars didn’t have the standardized three pedals, steering wheel, and gear shifter controls that most of us will know. Take the Ford Model T for example: to drive it in reverse you depress the middle pedal, its brake pedal is where a modern accelerator should be, and its throttle is on a lever on the steering column. It’s confusing to say the least. As cars got more advanced, driving them became an increasingly… This story continues at The Next Web
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This week, we discuss the growing trend of mid-range smartphones, why they’re good, and why they’re bad.
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The three-game series between the Cubs and the Cardinals starts tonight. Here's how to stream it live online.
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Chips that allow modern phone features, such as quick charging or noise cancellation, may open the door for hackers too, researchers warn.
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Earlier this week, Google parent Alphabet raised $10 billion despite already sitting on $121 billion in cash — a decision no doubt fuelled by the Fed’s souped-up money printer and record low interest rates. But the Mountain View giant is not alone; the rest of US tech is hoarding too. In 2012, the companies currently featured in the tech-heavy NASDAQ 100 (NDX) stock index collectively held $405 billion in cash and other small investments. Now, they’ve amassed more than $927 billion — more than half a trillion dollars saved in eight years. Microsoft and Alphabet are NASDAQ’s kings of cash As one might expect,… This story continues at The Next Web
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Photo by Matthew Horwood/Getty Images Virgin Atlantic Airways has filed for bankruptcy protection for its United States business, as it tries to nail down a £1.2 billion ($1.6 billion) rescue plan announced last month. It’s the second of Richard Branson’s airlines to do so during the COVID-19 pandemic, after Virgin Australia filed for “administration” — a form of bankruptcy in countries like Australia and England — earlier this year. Virgin Atlantic filed for Chapter 15 bankruptcy protection in the Southern District of New York on Tuesday. Chapter 15 is a way for foreign companies to let US bankruptcy courts recognize restructuring efforts happening abroad. The company is not yet going out of business or liquidating its operations, which is what Chapter 7 bankruptcy... Continue reading…
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What would a Poco-branded Nord challenger look like?
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Image: Samsung It’s all kicking off on August 5th at 10AM ET Continue reading…
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MediaTek has revealed that budget 5G phones powered by MediaTek SoC’s will be available outside China for the first time later this year.
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President Trump will make an announcement shortly, he added
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The Last of Us show was announced in early 2020 and will air on HBO
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The Razer BlackShark V2 and BlackShark V2 X are made for gamers at all levels. The BlackShark V2 is made to be the “definitive esports gaming headset” while the “X” version is meant to deliver JUST the essentials for a significantly lower price. If for no other reason than these headphones are exceedingly comfortable to wear for long periods of … Continue reading
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Huawei have been having a good year, despite COVID, and South Africans will now be getting even more from the company
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In the spring of this year, Xiaomi released its flagship smartphones Xiaomi Mi 10 and Xiaomi Mi 10 Pro, and now another model of this ... The post Xiaomi Mi 10 Pro Plus will be the best smartphone for all types of charging appeared first on Gizchina.com.
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Until the COVID-19 pandemic is over, survival has to be the imperative focus for startups. In this brief survival guide, we provide several tips for startups and their owners and managers to help them get through the crisis and stay in control of their companies. The pandemic is very different from the financial crisis in 2008. Not all firms are losing out, with the value of some companies increasing on the stock market and certain businesses experiencing more demand than they were prepared for. In fact, some companies are hiring. In contrast, many businesses cannot use their traditional supply and… This story continues at The Next Web
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We’re here to guide you through the coronavirus pandemic. Sign up to the Life newsletter for daily tips, advice, how-tos and escapism.With a vaccine not looking likely this side of Christmas, scientists and health experts are scrabbling to find existing drugs that can help fight against the worst effects of Covid-19.The Recovery trial in the UK has already unearthed one game-changing drug, dexamethasone, and has crossed two other treatments off the list after they didn’t show any clinical benefits. The first is hydroxychloroquine, the drug fiercely advocated for by Donald Trump despite studies showing it’s not effective; the other is lopinavir-ritonavir, a drug commonly used to treat HIV. Related... How Close Are We To Getting A Coronavirus Vaccine? More than 11,500 Covid-19 patients from over 175 NHS hospitals in the UK have been enrolled on the trial with a view to finding treatments that reduce deaths and the need for mechanical ventilation.Here’s what you need to know about the drugs currently being tested, as well as those already in use for treating the virus.RemdesivirWhat is it?Remdesivir is an antiviral drug that was originally developed to treat ebola but was dropped from trials after other drugs were found to be more effective.What’s the deal? The experimental drug, produced by US pharmaceutical company Gilead, was revived as a potential treatment for coronavirus after animal trials showed it had some impact fighting other strains of coronavirus: MERs and SARs.The aim of antiviral drugs is to directly target a virus (such as Covid-19) and either kill it or prevent it from spreading.The drug is being trialled worldwide with data suggesting it can shorten recovery time by approximately four days in hospitalised patients. Results have also shown a small trend toward better survival rates for the drug – 8% of patients given remdesivir died, compared to 11.6% in the placebo group. However, scientists admitted the difference wasn’t significant enough to be sure it was down to the effect of the drug. The Department of Health and Social Care has approved the drug for limited use in the UK, which means it will be made available to selected patients in NHS hospitals.Related... Am I Immune To Covid-19 – And How Would I Know? DexamethasoneWhat is it? Dexamethasone is a type of steroid that prevents the release of substances in the body that cause inflammation. It’s typically used to treat inflammatory conditions such as allergic disorders and skin conditions.What’s the deal? As part of the UK’s Recovery trial, 2,104 patients were given dexamethasone once a day for 10 days and outcomes compared with 4,321 patients receiving usual care. The steroid reduced deaths by one third in ventilated patients and by one fifth in other patients receiving oxygen. There was no benefit found among patients who did not require respiratory support.The drug works by suppressing the body’s immune response to Covid-19. This is important because in some people the immune system can go into complete overdrive and cause more havoc than the actual virus itself. As immunologist Dr Jenna Macciochi previously told HuffPost UK: “For some reason the natural brakes of our immune system fail and the inflammatory reaction overshoots.”This can result in blocked airways, overwhelmed organs, and can potentially lead to multi-organ failure and death. The steroid drug, however, is thought to suppress this process. Professor Peter Horby, an expert in emerging infectious diseases at University of Oxford and one of the chief investigators for the trial, said the survival benefit is “clear and large” in those patients sick enough to require oxygen treatment. Dexamethasone is the first drug shown to improve survival in Covid-19 and is already being used to tackle the virus by the NHS. Its use is still being studied in children and is not suitable for mild cases.Related... How Does Covid-19 Affect Your Immune System? SNG001What is it? SNG001 is an inhaled form of interferon beta, which is typically used to treat multiple sclerosis (MS). Interferon beta is a naturally occurring protein in the body which is made into a drug and used to reduce inflammation in the body.One of the key impacts of the coronavirus is suppressing the body’s production of interferon beta, Richard Marsden, CEO of Synairgen, the company behind SNG001, told the BBC. The aim of the drug is to put the protein straight into the lungs of Covid-19 patients to help give them a fighting chance. What’s the deal? A small clinical trial of the drug found it stopped the disease from progressing and in some cases sped up recovery. Patients who received SNG001 had a 79% lower risk of developing severe disease compared to placebo, and were more than twice as likely to recover from Covid-19 compared to those taking a placebo.Over the treatment period, the measure of breathlessness was markedly reduced in patients who received SNG001 compared to those receiving the placebo. And there were no deaths among subjects treated with SNG001, compared to three from the placebo group.The results haven’t been published in a peer-reviewed journal yet.AzithromycinWhat is it? A commonly used antibiotic with antiviral and immunomodulatory properties (which basically means it modifies the immune response or the functioning of the immune system). It’s traditionally used to treat different types of infections caused by bacteria, such as respiratory infections, skin infections, ear infections, eye infections, and sexually transmitted diseases.What’s the deal? Most studies to date have been conducted on hydroxychloroquine and azithromycin as a combination, so it’s been hard to gauge the drug’s potential as a treatment on its own. The reason it’s being trialled is because it’s thought azithromycin might have potential when it comes to handling the body’s immune response to Covid-19 and preventing it from going into overdrive (a key factor in most of treatments being trialled.)Professor Martin Landray, an expert in medicine and epidemiology at the Nuffield Department of Population Health, University of Oxford, and deputy chief investigator of the Recovery trial, tells HuffPost UK: “Azithromycin is a macrolide antibiotic. In addition to their antimicrobial properties, macrolide antibiotics modify the response of the immune system by decreasing the production of cytokines, proteins that cause inflammation. In some patients, excessive levels of cytokines are released, resulting in a ‘cytokine storm’, a complication of Covid-19 which can kill the patient.“We hope that azithromycin will show positive benefit for hospitalised Covid-19 patients but whether there is a benefit can only be determined by testing the treatment through a randomised controlled trial. We do not anticipate results until later in the year.”Some experts are sceptical of whether the antibiotic will work. Writing in the journal Open Forum Infectious Diseases in June, Dr Jennifer Lighter and Dr Vanessa Raabe from New York University’s School of Medicine argued there is “no justifiable preclinical or clinical evidence” to suggest that the benefits of azithromycin for Covid-19 outweigh the risks of treatment, and warned that clinicians should stop prescribing it.Related... These 'Distance Aware' Badges And Lanyards Let Others Know To Keep 2m Away TocilizumabWhat is it? An anti-inflammatory treatment given by injection. It’s normally used to treat moderate to severe rheumatoid arthritis in adults, as well as cytokine release syndrome (CRS), which is caused by an overactive immune response to certain types of blood cell treatments for cancer. What’s the deal? Tocilizumab is currently being trialled in the UK, and the timing of the results will depend on the scale of the epidemic in the coming months, Professor Landray tells HuffPost UK. The drug has had a promising impact in Italy where a study of adults with severe Covid-19 pneumonia who were admitted to hospital during the height of the pandemic found that out of 544 patients with severe Covid-19 pneumonia, 16% of patients in the standard care group needed mechanical ventilation, compared with 18% of patients treated with tocilizumab.One in five patients (20%) in the standard care group died, compared with 7% of patients treated with tocilizumab. The study’s authors concluded that treatment with tocilizumab “might reduce the risk of invasive mechanical ventilation or death in patients with severe Covid-19 pneumonia”.One concern is that taking the drug can lead to other bacterial infections in the body. The same study from Italy found 13% of patients treated with tocilizumab were diagnosed with new infections, compared with only 4% of patients treated with standard of care alone.Convalescent PlasmaWhat is it? Convalescent plasma is collected from donors, via their blood, who have recovered from Covid-19 and contains antibodies which help fight against the virus. The hope is that this antibody-rich plasma can be donated by recovered Covid patients and transfused into infected patients whose immune systems are struggling to fight the infection.What’s the deal? There is some limited evidence that patients might benefit from the use of convalescent plasma. Clinical trials are now underway in the UK to confirm whether transfusions are safe and effective for treating Covid-19.The first transfusion happened back in June and was given to a child – since then 300 people have received plasma. Professor Landray says: “We anticipate that much larger numbers will be needed before we have a clear result. Like the other treatments we are studying, there are good theoretical reasons to believe this treatment may be beneficial – but we need the evidence from this large randomised trial before we will know whether that hope is translated into real benefits for patients.”NHS Blood and Transplant is appealing for people who have recovered from Covid-19 or the symptoms, and who live near one of its 23 donor centres, to offer to donate their plasma by calling 0300 123 23 23 or visiting www.nhsbt.nhs.uk.Plasma donations from men are particularly welcomed, as figures show that 43% of male blood plasma donors have high antibodies, compared to 29% of women. Explaining why men might have a higher antibody count, Professor David Roberts, from NHS Blood and Transplant, said: “Our studies and many others around the world show men with Covid-19 are more likely to become seriously ill than women. This makes them better plasma donors once they’ve recovered.”Researchers anticipate results from the plasma trial in the last quarter of 2020.Related... WHO Warns Coronavirus Pandemic Will Be 'One Big Wave' What We Know About The Long-Term Impact Of 'Mild' Covid-19 Flu Vaccine To Be Offered Free To 'Millions More' – Are GPs Ready?
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Real-time information on supply and demand and electricity pricing will improve how we use the grid
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Apple's Tim Cook, Facebook's Mark Zuckerberg, Google's Sundar Pichai, and Amazon's Jeff Bezos are testifying on Wednesday before Congress on antitrust issues. But there's another issue at top tech companies that's going unaddressed — the wage gap between men and women.   Women are offered 3% less money than men for the same tech job at the same company, according to 2019 data from Hired, a job website that focuses on placing people in tech jobs. A report by business price comparison website Small Business Prices analyzed self-reported salary data from several large tech employers. The report showed that, in general, women earn less than then men at some of the world's top tech companies. This could be attributed to the fact that high-paid software engineers are more likely to be male than female.   Visit Business Insider's homepage for more stories. Sign up here to receive updates on all things Gender at Work. Apple's Tim Cook, Facebook's Mark Zuckerberg, Google's Sundar Pichai, and Amazon's Jeff Bezos are testifying on Wednesday before Congress to defend their business practices and argue they're not so big that they're stifling competition. It's an important issue, but it's not the only one these tech CEOs face.  Another big issue is the clear pay differences between men and women in the industry. A look at salary data from the world's top tech companies shows that, despite efforts to achieve equal pay, the wage gap persists.  On average, a woman working full time earns 80.7 cents for every dollar a man working full time earns. Women's median annual earnings are $9,909 less than men's, according to data from the US Census Bureau. And in tech, women are offered 3% less than men for the same job at the same company in, according to 2019 data from Hired, a job website that focuses on placing people in tech jobs. Using self-reported salary data from PayScale, a salary website and software company, analysts from Small Business Prices, a business price comparison website, looked at salary info for 10 Fortune 100 tech companies. They compared the salary data for men to women and found, on average, a consistent trend. For the most part, men consistently reported earning more than women. This data was self reported by employees and may change over time. The difference may be attributed to the fact that software engineers at tech companies, which make some of the highest salaries, are more likely to be male than female, as the data encompassed salary data for all roles at a company.  Here's how men and women's self-reported salaries compare at some of the world's top tech companies, ranked by the difference between men and women's reported salaries, with companies listed in order of how big the gender wage gap is. At all firms except for one, men self-report higher salaries than women.SEE ALSO: The 15 coding languages with the highest salaries, and how to learn them online at no cost Women at Facebook make $17,000 less than their male counterparts. Average salary: $120,000 Average men's salary: $129,000 Average women's salary: $112,000 Women at PayPal make $12,000 less than their male counterparts. Average salary: $111,000 Average men's salary: $118,500 Average women's salary: $106,500 Women at Apple make $12,000 less than their male counterparts. Average salary: $123,000 Average men's salary: $121,000 Average women's salary: $109,000 Women at Oracle make $11,500 less than their male counterparts. Average salary: $109,000 Average men's salary: $116,000 Average women's salary: $104,500 Women at Google make $11,500 less than their male counterparts. Average salary: $115,000 Average men's salary: $120,000 Average women's salary: $109,000 Women at Cisco make $9,500 less than their male counterparts. Average salary: $106,000 Average men's salary: $112,500 Average women's salary: $103,00 Women at Microsoft make $5,500 less than their male counterparts. Average salary: $119,000 Average men's salary: $119,000 Average women's salary: $113,500 Women at eBay make $5,000 less than their male counterparts. Average salary: $124,000 Average men's salary: $119,500 Average women's salary: $114,500 Women at Visa make $3,000 less than their male counterparts. Average salary: $109,000 Average men's salary: $115,000 Average women's salary: $112,000 Women at Adobe make $21,000 more than their male counterparts. Average salary: $104,000 Average men's salary: $105,500 Average women's salary: $126,500
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(American Institute of Physics) Many compact systems using mid-infrared technology continue to face compatibility issues when integrating with conventional electronics. Black phosphorus has garnered attention for overcoming these challenges thanks to a wide variety of uses in photonic circuits. Research published in Applied Physics Reviews highlights the material's potential for emerging devices ranging from medical imaging to environment monitoring, assessing progress in different components of the chips, from light detection to laser emission.
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In recent weeks, Apple introduced enterprise-focused updates at WWDC, Jamf filed its hugely successful IPO and Apple acquired Fleetsmith. This frenetic Apple-in-the-enterprise activity is generating lots of conversation. I spoke with Addigy founder and CEO Jason Dettbarn,to get his take on mobility, IT and Apple’s growing place in enterprise tech.To read this article in full, please click here
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Due to the pandemic, the continuing zombie apocalypse has been postponed from August 2020.
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Obsidian reveals Avowed, a first-person game set in the Pillars of Eternity universe.
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From defense contractors to videogame companies, the indictment details an astonishing array of victims.
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What do you do when you can’t go to the doctor’s office? As the COVID-19 pandemic has forced people around the world to stay at home and avoid crowded and possibly contaminated areas, this has become a big concern. The pandemic has spurred a new wave of innovation, shedding new light on online diagnosis and remote care technologies that have been around for a while but have been limited to the doctor’s office. The Dutch startup community, one of the fastest-growing technology hubs in Europe, has played a key role in developing new tools and facilities to make sure doctors can… This story continues at The Next Web
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There seems to be some confusion when it comes to JavaScript modules. Some developers are unsure of how they work and why are various ways that they can be used. To clear up some of these misconceptions, this article will explain the different ways in which you can export and import modules. First, let’s explore background of JavaScript modules. JavaScript programs started as simple scripts or apps that had rather small codebases. But after time, its evolved and so has its uses meaning there’s been an increase in the size of codebases. To support this increase the language needed to support… This story continues at The Next Web
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(American Association for the Advancement of Science) AAAS is launching the Science Partner Journal, Cyborg and Bionic Systems, published in affiliation with the Beijing Institute of Technology (BIT).
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As were the morons whose illegal party was rumbled when they made a colossal KFC order Police in the Australian state of Victoria have fined Pokémon Go players for venturing out during COVID-19 quarantine.…
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Gym rats and fitness newcomers alike will be able to work up a sweat with these pulse-quickening game titles.
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Stream Aladdin to see Disney take an animated classic and make it into a live-action phenomenon for all ages.
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This post explains how to concatenate a string in Python.
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