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Solubilization technologyAt present, most of the methods for improving the solubility of drugs on the market are mainly drug solubilization methods, including ①pH adjustment method: suitable for some weakly acidic and weakly basic drugs, by adjusting the pH value to increase the solubility of the drug; ②mixed solvent method: add a certain proportion of organic solvents (ethanol, glycerol, ethylene glycol, polyethylene glycol, etc.)

Nanocrystals technologyDue to the toxicity of solvents and surfactants, traditional drug solubilization methods are limited, so some drugs cannot achieve sufficient dosage concentrations.

In recent years, drug nanocrystals are a new type of nano drug delivery system.

Because nano-level drug crystals have a large specific surface area, according to the Ostwald-Freundlich and Noyes-Whitney formulas, this technology can effectively increase the saturated solubility of the drug, greatly improve the bioavailability, and reduce the dosage of the drug to a certain extent, thereby reducing the occurrence of adverse reactions.

In December 2015, a dry suspension of aprepitant was developed by a pharmaceutical company for pediatric patients from 6 months to 12 years old and was approved by the FDA for marketing.

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Eating deep sea fish 3 times a week, or taking at least 2000 mg of a contaminant-free fish oil capsule each day, is beneficial.

Usually this includes eating either two or three meals within this 8-hour period.

They trigger your insulin levels to quickly spike after which crash every time you eat considered one of these foods.

Project portfolio management (PPM), also known as digital asset management (DAM), is an industry-standard approach that enables companies to effectively manage and monitor their digital assets.

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Portfolio Management Software (PMS) is designed to automate the process of prioritizing tasks, while identifying those projects that meet specific needs and are of the highest importance to the company.Portfolio Management Software has been proven to enhance collaboration among team members and departments while significantly reducing overall costs.

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