Knockout Mice Model Market: Overview
Unexpected and unforeseen public health emergency brought on by the COVID-19 pandemic is expected to further the growth of the global knockout mice model market in coming years. This trend can be attributed to the increasing need for development of effective and novel antiviral drugs and vaccines intended to diminish the novel coronavirus. As a stage in new drug discovery process, undertaking a massive number of animal models testing is required and deemed as an essential process prior to engaging in human trials. This stage assists researchers to test efficacy and safety of the discovered or designed drug before starting to experiment on human subjects. This is expected to create numerous opportunities for the global knockout mice model market. As this stage is absolutely essential in the development process of any antiviral and antibiotic drugs and vaccines, every company and research organization has to avail services from the global knockout mice model market during the pre-clinical stage in the discovery.
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World Health Organization or WHO states that over 20 vaccines are being developed for COVID-19 all over the world, some of which have already started the animal trial phase. Rising need for effective COVID-19 vaccines to control the pandemic situation and eradicate the virus is expected to boost the global knockout mice model market in the near future. Increasing government initiatives and investments to discover effective vaccines and treatment medications is also expected to stimulate growth in global knockout mice model market in coming years.
A knockout mouse is a laboratory mouse (a biological model) in which a target gene has been disrupted or inactivated. The loss of gene activity frequently results in changes in the mouse's phenotypic characteristics (behavior, appearance, and other observable biochemical characteristics). This, in turn, allows in vivo studies of gene function, disease research, and drug development. Knockout mice are a powerful tool for analyzing gene function during development and in disease process.
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Emergence of CRISPR as a powerful tool in the field of biomedical research, rising burden of obesity, increasing prevalence of cancer, cardiovascular diseases, diabetes, autism, schizophrenia, and rare diseases are some of the pivotal factors that are anticipated to propel the demand of knockout mice models in the near future.
Incessant grants/funds supporting cancer research studies, agreements & collaborations strengthening cancer research, increasing biomedical research activities in prominent markets such as the U.S., Australia, rising pharmaceutical & biotechnology R&D activities in Korea, increasing translational and biomedical research in Singapore, international alliances for R&D activities, growing public and private investments in life sciences sector, upsurge in animal research in Malaysia, growing pharmaceutical, biotechnology & research industries in Brazil, Saudi Arabia and the UAE are other driving factors that are expected to provide impetus to the market.
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Increasing focus of associations such as International Mouse Phenotyping Consortium (IMPC) & International Knockout Mouse Consortium (IKMC) on the development of knockout mice is likely to unlock new areas of biology and lead to novel drug target discovery. .
In terms of types, the knockout mice models market has been divided into conditional knockout, constitutive knockout, inducible knockout, and tissue-specific knockout. Conditional knockout mice models are made by engineering recombinase specific targets. This enables the deletion of a gene in a tissue- and time-specific manner. Constitutive knockout mice models are created to carry an inoperative gene. It permanently inactivates a target gene in every cell of the organism. Inducible knockout mice models are conditional biological models, in which target gene of interest can be inactivated at a given point of time. It inactivates gene expression in a time-controlled manner. Tissue-specific knockout mice models are conditional biological models, in which target gene can be inactivated in a specific tissue or tissues such as the brain, intestine, muscles, skin, and all the other tissues.
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In terms of type of indications, the knockout mice model market has been further classified into obesity, cancer, cardiovascular diseases, diabetes, neurological disorders, and others. Knockout mice models for cancer, cardiovascular diseases, diabetes & neurological disorders segments are well-established and hence their availability for these indications is not a concern. However, the supply of knockout mice models for neurological disorders and rare diseases is low; therefore, their availability for these indications is a concern. The knockout mice models for obesity, cancer, cardiovascular diseases, diabetes are priced relatively lower than the knockout models for neurological disorders and rare diseases due to the demand-supply gap. Based on geography, the knockout mice model market is segment into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa.
Key players operating in the global knockout mice model market are Charles River Laboratories, Inc., The Jackson Laboratory, ENVIGO (Harlan Laboratories, Inc.), Taconic Biosciences, Inc., genOway, Cyagen Biosciences, Inc., Horizon Discovery Group PLC (Sage Labs, Inc.), Deltagen (TRANS GENIC INC.), and Ozgene.
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Global Humanized Mice Model Market: OverviewThe healthcare industry, despite facing vast political and economic uncertainty in the past few years, continues to remain dynamic when it comes to funds being diverted to the R sector and the introduction of novel and technologically advanced medical devices, medical imaging equipment, and pharmaceutical and biopharmaceutical products.
Attempts to engraft mouse bone marrow with human hematopoietic stem cells and mouse liver with human hepatocytes, allowing them to overcome the limitations of the conventional xenograft models, has also provided new opportunities to the market.
Global Humanized Mice Model Market: Trends and OpportunitiesThe rising demand from the healthcare sector for more effective screening of new drug candidates discovered to treat a variety of chronic diseases such as cardiovascular conditions, diabetes, and cancers, has remained one of the leading factors driving increased research activities in the field of humanized mice models.
The consecutive rise in competition has also compelled companies to focus more on R activities aimed at the development of more reliable mice models that can improve the outcomes of research studies.Request COVID Analysis on Humanized Mice Model Market – https://www.transparencymarketresearch.com/sample/sample.php?flag=covid19_id=49656Moreover, the market benefits from the fact that humanized mice models are better research tools as compared to mutant mouse protein.
Humanized mice models are considered more realistic for studying tumors as compared to cultured cancer cells and also find usage for evaluating the safety of certain biologics when neither rats nor normal mice are useful.
The key end users of humanized mice models examined in the report include contract research organization, pharmaceutical and biotechnology companies, and academic and research institutions.
The Global Mice Model Market Research Report - Industry Analysis, Size, Share, Growth, Trends and Forecast Till 2026 gives an evaluation of the market developments based on historical studies and comprehensive research respectively.
The market segments are also provided with an in-depth outlook of the competitive landscape and a listing of the profiled key players.The comprehensive value chain analysis of the market will assist in attaining better product differentiation, along with detailed understanding of the core competency of each activity involved.
The market attractiveness analysis provided in the report aptly measures the potential value of the market providing business strategists with the latest growth opportunities.The report classifies the market into different segments based on type, specialty and services.
These segments are studied in detail incorporating the market estimates and forecasts at regional and country level.
The segment analysis is useful in understanding the growth areas and probable opportunities of the market.Final Report will cover the impact of COVID-19 on this industry.Browse the complete Global Mice Model Market Research Report – Industry Analysis, Size, Share, Growth, Trends and Forecast Till 2026 @ https://www.decisiondatabases.com/ip/15746-mice-model-market-reportThe report also covers the complete competitive landscape of the global Mice Model market with company profiles of key players such as:Charles River Laboratories International, Inc.Crescendo Biologics LimitedDeltagen, Inc.genOway S.A.Harbour Antibodies BVHarlan Laboratories, Inc.ImmunoGenes AGSAGE LabsThe Jackson LaboratoryTaconic Biosciences, Inc.TransGenic, Inc.A detailed description of each has been included, with information in terms of H.Q, future capacities, key mergers & acquisitions, financial overview, partnerships, collaborations, new product launches, new product developments and other latest industrial developments.SEGMENTATIONS IN THE REPORT:By Type:Transgenic Mice ModelHybrid/Congenic Mice ModelKnockout Mice ModelCarcinogen-induced and Spontaneous Mice ModelOutbred Mice ModelInbred Mice ModelTransplantation Mice ModelConditioned/Surgically Modified Mice ModelBy Specialty:ImmunologyCentral Nervous System (CNS)OncologyCardiovascularDiabetesMetabolism & RegulationBy Services:Breeding and Rederivation ServicesCryopreservation and Cryorecovery ServicesQuarantine ServicesGenetic Testing ServicesModel In-licensing ServicesIn vivo and In vitro Pharmacology ServicesGenetically Engineered Model ServicesOther Services (Surgical and Line Rescue)By Geography:North America (NA)Europe (EU)Asia Pacific (APAC)Latin America (LA)Middle East & Africa (MEA)Download Free Sample Report of Global Mice Model Market @ https://www.decisiondatabases.com/contact/download-sample-15746The Global Mice Model Market has been exhibited in detail in the following chapters –Chapter 1 Mice Model Market PrefaceChapter 2 Executive SummaryChapter 3 Mice Model Industry AnalysisChapter 4 Mice Model Market Value Chain AnalysisChapter 5 Mice Model Market Analysis By TypeChapter 6 Mice Model Market Analysis By SpecialtyChapter 7 Mice Model Market Analysis By ServicesChapter 8 Mice Model Market Analysis By GeographyChapter 9 Competitive Landscape Of Mice Model CompaniesChapter 10 Company Profiles Of Mice Model IndustryPurchase the complete Global Mice Model Market Research Report @ https://www.decisiondatabases.com/contact/buy-now-15746Other Reports by DecisionDatabases.com:Global Humanized Mouse Model Market Research Report – Industry Analysis, Size, Share, Growth, Trends and Forecast Till 2026Global Animal Model Market Research Report – Industry Analysis, Size, Share, Growth, Trends and Forecast Till 2026About-Us:DecisionDatabases.com is a global business research reports provider, enriching decision makers and strategists with qualitative statistics.
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