The conventional low-priced mainstay drugs for the treatment of malaria, sulphadoxine-pyrimethamine (SP) and chloroquine (CQ), are witnessing a decline in sales, as they are becoming comparatively ineffective. During the last two decades in Asia, the issue has become a major concern. This has resulted in the adoption of artemisinin (derived from the Chinese herb Artemisia annua) in Africa as a standard treatment. It helped in setting a milestone for the artemisinin combination therapy market. The herb has been used to treat fevers and malaria for more than 2000 years. The World Health Organization (WHO) has adopted artemisinin-based combination therapy (ACTs) as the first-line treatment for plasmodium falciparum malaria. As a combination therapy, it has demonstrated superiority to other drugs because of its ability to wipe out parasites and its life cycle stages faster. Its use with cancer transferrin to cure cancer is also adding value to the artemisinin combination therapy market.
Triple ACTs (TACTs) combine with artemisinin and two other existing partner drugs to work effectively as stop-gap therapy for the treatment of multidrug-resistant malaria. It will be used till the arrival of new antimalarial drugs. TACTs are secure, competent, well-accepted, and economical. This artemisinin combination therapy is likely to gain wider acceptance among the target consumers. The barriers in the deployment should be identified and stakeholders should make efforts to overcome them, which will new growth avenues in artemisinin combination therapy market.
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Artemisinin Combination Therapy Market Introduction
Artemisinin is a plant derivative isolated from Artemisia annua, or sweet wormwood, which is known to effectively and swiftly reduce the number of plasmodium parasites in the blood of malaria patients. The WHO recommends artemisinin combination therapies (ACTs) as the first line of treatment for uncomplicated plasmodium falciparum malaria and as the second line of treatment for chloroquine-resistant P. vivax malaria.
This therapy combines an artemisinin derivative along with a partner drug, wherein artemisinin aids in reducing the number of parasites and the partner drug eliminates the remaining parasites. Efficacy of the treatment is determined by the drug combined with artemisinin, such as artesunate-mefloquine, dihydroartemisinin–piperaquine, and artemether-lumefantrine.
Falciparum malaria was one of the most common lethal infections which was treated with chloroquine and sulfadoxine-pyrimethamine. However, these drugs are not effective as treatment primarily in the tropical regions owing to the resistance developed against these drugs. According to the Medicines Malaria Venture (MMV), over 445,000 deaths were reported in 2016 due to malaria. The globally rising malaria endemic and the changing climatic conditions would contribute to the trend aiding in the artemisinin combination therapy market growth.
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Artemisinin Combination Therapy Market- Competitive Landscape
The strategies adopted by the market players to enhance their market position include indication extension, focus on geographic expansion, and research & development. The national funding allocations, as announced by the Global Fund for 2018-2020, report that the funding available for the promotion of malaria programs is around US$1 billion.
Novartis AG
Novartis AG, established in 1895, is engaged in research, development, manufacturing and marketing of healthcare products across a range of areas, including neuroscience, ophthalmology, immunology, hepatology, respiratory, cardiology, dermatology, and cardio metabolic.
Sanofi
Sanofi, a leading pharmaceutical company is engaged in the manufacturing of prescription pharmaceuticals and vaccines. It is engaged in the development of cardiovascular, metabolic disorder, central nervous system (CNS), oncology, and thrombosis drugs and medicines.
Ipca Laboratories Ltd.
Ipca Laboratories is an Indian pharmaceutical company engaged in the manufacturing of over 350 formulations and 80 APIs for a range of therapeutic indications. According to the company, it is the market leader in India for anti-malarials with a market share of over 34% in 2018.
Artemisinin Combination Therapy Market - Dynamics
Growing malaria endemic
Malaria is a major health concern in endemic countries such as Sudan, wherein over 75% of the population is at the risk of acquiring the disease. Moreover, the widespread presence of chloroquine-resistant strains of P. falciparum in the malaria endemic countries makes artemisinin combination therapy the preferred choice of treatment. This is projected to fuel the growth of the artemisinin combination therapy market.
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Increase in the procurement of ACT treatment courses
Increase in access to ACTs in the malaria-endemic countries contributes to the rising success in reducing the global malaria burden. According to the WHO, over 2.7 billion ACT treatment courses were procured by global countries between 2010 and 2017. Moreover, over 62% of these procurements were made by the public sector. Strong pipeline for the development of new anti-malarial drugs and launch of newer artemisinin combinations for the treatment of malaria boost to the growth of the global artemisinin combination therapy market.
Challenges related to the availability of raw materials
Challenges pertaining to the availability of intermediate products and raw materials in the production of artemisinin-based combination therapies from agricultural sources are expected to restrain the global artemisinin combination therapy market. Furthermore, volatility in the artemisinin market leading to concerns over supply tightening could create significant risks to patients and market participants.
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Barium, a chemically inert and dense mineral, is used in a number of end-use industries.
It is also quite interesting to note that not only are certain areas identified as hotbeds of exploration, they are also highly productive.” Some of these are the Mediterranean region, Africa, and Latin America.In terms of BOE (Barrels of Oil Equivalent), the new regions show a performance of 26 discoveries - 100 BOE, out of the 12.2 billion barrels BOE discovered in 2019.
This shows how conventional discoveries are moving on a high trajectory.The study report on the global barite market, prepared by Transparency Market Research states that the market would chart a decent CAGR (Compound Annual Growth Rate) of 4.8 percent – in the period 2018-2026 Request Sample pages of premium Research Report: https://www.transparencymarketresearch.com/sample/sample.php?flag=B_id=2404Consolidated Vendor Landscape to Mark Global Barite Market over the Forecast PeriodThe competitive landscape of the global barite market is consolidated and the trend will continue over the forecast period.
Apart from improving the product quality, players are looking to work with different grades in order to widen the scope of applications.Some of the players that are seen as high performers in the global barite market include Spectrum Chemical Manufacturing Corporation, Deutsche Baryt Industrie, Halliburton, CIMBAR Performance Minerals, New Riverside Ochre Company, Inc., Excalibar Minerals LLC, and Anglo Pacific Minerals, among others.It is pertinent to note here that the top tier players that are operating in the global barite market landscape have a hold on about 55% of the total market share.
It is also important to note that these players are scurrying to improve plant facilities for bettering capacity in terms of production.North America to Show Stellar Performance over the Forecast PeriodDominating the regional landscape of the global barite market, North America will ride to growth on the back of strong presence of key market players and numerous end-use industries in its landscape.
However, market expert’s note, “Oil and gas segment in the region will lose to rubber and plastics over the period to come.”Request for covid19 Impact Analysis - https://www.transparencymarketresearch.com/sample/sample.php?flag=covid19_id=2404About UsTransparency Market Research is a next-generation market intelligence provider, offering fact-based solutions to business leaders, consultants, and strategy professionals.Our reports are single-point solutions for businesses to grow, evolve, and mature.
The global electrical appliances market was valued at around US$ 685 Bn in 2016 and is anticipated to register a CAGR of ~7% from 2017 to 2025, according to a new report by Transparency Market Research (TMR) titled “Electrical Appliances Market- Global Industry Analysis, Size, Share, Growth, Trends, and Forecast, 2017–2025.”Electrical appliances are defined as devices which use electricity to perform specific functions.
A wide range of such appliances is available from refrigerators, wine-coolers, washing machines, tumble dryers, vacuum cleaners, steam mops, shavers, trimmers and water heaters to air conditioners, air coolers, heaters, fans, rice cookers, bread makers, toasters, irons, and juicers.
Interpret a Competitive outlook Analysis Report with PDF Brochure - https://www.transparencymarketresearch.com/sample/sample.php?flag=B_id=41387Higher standards of living and availability of lucrative product offers and purchase credit schemes to drive the market for electrical appliancesOne of the primary drivers of the market is higher standards of living, especially in the Asia Pacific region.
The major restraint on the global electrical appliances market is the consistent and considerable R investment required to develop new, more efficient, environment-friendly, smart, and connected appliances.
It is a highly competitive market coupled with increasingly stringent government regulations regarding emissions of environmentally harmful chemicals.
In such a scenario, the constant improvement of products is important, though this is mostly possible only by the larger companies such as Whirlpool Corporation, Haier Group, and LG Electronics Inc.Product differentiation and new product development are expected to be among the available opportunities in the global electrical appliance market during the forecast periodMajor opportunities in the global electrical appliances market exist in product differentiation and new product development.
The global hospital acquired pneumonia drug market has been analyzed by Transparency Market Research (TMR) to give a complete description of the market and its growth in the coming years.
Few vendors are likely to adopt pricing strategies that would increase the competition in the market.Request Brochure of Report - https://www.transparencymarketresearch.com/sample/sample.php?flag=B_id=1881Furthermore, companies are likely to adopt strategies such as high investments to adopt newer technologies, research and development activities, and mergers and acquisitions to strengthen their position in the market.
North America is expected to lead the market during the forecast period.
The presence of large number of vendors has also made the North America market grow distinctively.Request for Analysis of COVID-19 Impact on Hospital Acquired Pneumonia Drugs Market - https://www.transparencymarketresearch.com/sample/sample.php?flag=covid19_id=1881Immunocompromised Patients Are Prone to Acquire Pneumonia from hospitals Patients who have undergone a surgery, are on enteral feeding, or are immunocompromised are more vulnerable to acquiring hospital acquired pneumonia.
The hospital acquired pneumonia is also prevalent among the newborns, as they might suffer from respiratory syncytial virus (RSV) which has been identified as one of the major reason for nosocomial pneumonia.The increasing incidence of hospital acquired pneumonia has pushed the government to take effective and strict measures that can address the root cause of these types of infections.
The factors that create an unhealthy environment are often caused due to inadequate financial resources, poor infrastructure, and over-crowded hospitals that increase the chances of communicable diseases.
Upper respiratory tract infection (URTI) is a medical condition caused by acute infection that involves parts of the upper respiratory tract such as larynx or pharynx, sinuses, and nose.
Pharyngitis, sinusitis, laryngitis, tonsillitis, common cold, and otitis media are some of the most common upper respiratory tract disorders.
Some other symptoms of the disease are headaches, hyposmia, foul breath, sinus pain, shortness of breath, vomiting, diarrhea, nausea, conjunctivitis, and body ache.Request Brochure – https://www.transparencymarketresearch.com/sample/sample.php?flag=B_id=58905Upper respiratory tract disorders can be treated with antibiotics and decongestants.
Antibiotics are rarely used as a treatment option for upper respiratory tract disorders as they are associated with many side effects and also can initiate secondary infections and bacterial resistance.
The global upper respiratory tract infection treatment market is expected to expand substantially, due to an increase in the incidence of respiratory disorders across the globe.
However, side effects of NSAIDs are expected to impact the growth of this market.
Transparent Market Research (TMR) reflects the competitive landscape of the global pharmaceutical chemical spread across the globe.
New strategies are expected to be introduced to penetrate into the market.
Rising population and low mortality rate seems to be the reason for lucrative growth in the healthcare sector.
Swell in the geriatric population calls for increase in healthcare facilities.
Global pharmaceutical chemical market is projected to be flourishing in coming years due to rise in demand for drugs for non-communicable diseases.
However, developments in all the fields of healthcare facilities and rising geriatric population is projected to inflate the global pharmaceutical chemical market.Request for covid19 impact analysis –https://www.transparencymarketresearch.com/sample/sample.php?flag=covid19_id=37685Disease Oriented Treatment to Push GrowthVarious therapy based applications are expected to increase the demand for global pharmaceutical chemical market.
Asphalt Additives Market: Key HighlightsThe global asphalt additives marketwas valued at ~ US$ 3.5 Mn in 2018, and is projected to expand at a CAGR of ~ 6% from 2019 to 2027.
Emerging warm mix asphalt (WMA) technology is anticipated to augment the global asphalt additives market during the forecast period.Asia Pacific was the leading region of the global asphalt additives market in The Asia Pacific asphalt additives market is estimated to continue its dominance in the global asphalt additives market during the forecast period.Key Drivers of the Asphalt Additives MarketThe demand for asphalt in road construction is expected to be driven by increasing environmental funding, legislative pressure to improve infrastructure, and growth in non-building construction activities, particularly in the highway & street segment.The demand for paving asphalt used in highways and streets has been rising, owing to the increase in government funding and growth in highway and street construction activities.
Request a Sample – https://www.transparencymarketresearch.com/sample/sample.php?flag=S_id=3238Shift in Focus Toward Bio-based Additives to Offer Attractive OpportunitiesBio-based additives are defined as additives made from biological sources.
Manufacturers are increasingly using eco-friendly products, owing to the rise in the awareness about the environment among consumers.Availability of Alternatives for Asphalt to Hamper the Asphalt Additives MarketBricks, pavers, cobblestone, concrete, permeable paving, gravel, and cement are some of the substitutes that are being increasingly used in place of bitumen.
Concrete is a highly employed product in the construction and maintenance of roads.The governments of several countries have been preferring the usage of concrete and cement for paving roads since the last few years.
This is expected to hamper the asphalt additives market.Asia Pacific Dominates the Asphalt Additives MarketAsia Pacific is expected to continue being a prominent market in the global asphalt additives market during the forecast period.
