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Everything you wanted to know about Obesity Management Drugs

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Sharvari Gaikwad
Everything you wanted to know about Obesity Management Drugs

Obesity is defined using an index devised by the World Health Organization. The body mass index (BMI) is calculated by multiplying the patient's height in metres by his or her weight in kilogrammes: BMI (Body Mass Index) is a measurement of a person's weight in kilogrammes (height in meters). Except for individuals at the extremes of height or muscle mass, where body proportions impact the computation, this categorization works for all patients.


Obesity is a rapidly spreading epidemic that contributes significantly to the global burden of illness. Obesity management drugs puts a load on healthcare systems and has significant economic and emotional implications. Several promising medication candidates have come and gone in the history of obesity pharmacotherapy, all of which had to be removed owing to unacceptable safety concerns. Orlistat, lorcaserin, phentermine/topiramate extended release, and naltrexone/bupropion extended release are the four medicines now authorised for chronic weight control in obese people.


Causes:

  • Obesity develops when you consume more calories than you burn via regular everyday activity and exercise, despite genetic, behavioural, metabolic, and hormonal factors on body weight. These extra calories are stored as fat in your body.

     

  • Most people's diets in the United States are excessively calorie-dense, owing to fast food and high-calorie drinks. Obese people may consume more calories before feeling satisfied, feel hungry sooner, or eat more as a result of stress or worry.

     

  • Many individuals in Western nations today work in professions that aren't as physically demanding, therefore they don't burn as many calories at work. Because of the convenience, even daily tasks require less calories.


If you're battling with your weight, a well-balanced diet and regular physical activity will help you lose weight and keep it off in the long run. If lifestyle modifications alone aren't enough to help you lose weight and keep it off, your doctor may prescribe medications as part of your weight-loss plan.


The interaction of nature and nurture has a role in the development of obesity. In resource-limited situations, where energy saving was critical for life, genetic traits that incline people to obesity were probably favourable. These adaptive reactions result in needless retention of energy-rich adipose tissue as a result of modern settings supplying inexpensive energy-dense meals mixed with increasingly sedentary lifestyles. Obesity-related morbidity and mortality from diseases such as type 2 diabetes, cardiovascular and liver disease, and malignancies are thought to be caused by this increased bulk and the released chemokines.


A increasing amount of data shows that maternal obesity may enhance the likelihood of kids to become obese as adults due to epigenetic changes in foetal physiology. This is especially significant in the United Kingdom, where one in every five women of reproductive age is fat, because failing to treat maternal obesity might result in developmental programming consequences, exacerbating the pandemic.

Read more @ https://www.tradove.com/blog/1-Obesity-Management-Drugs-Current-status-and-future-prospects.html

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