1. About paracetamol for adults
Paracetamol is a common painkiller used to treat aches and pain. It can also be used to reduce a high temperature.
It's available combined with other painkillers and anti-sickness medicines. It's also an ingredient in a wide range of cold and flu remedies.
For under-16s, read our information on paracetamol for children.
2. Key facts
Paracetamol takes up to an hour to work.
The usual dose of paracetamol is one or two 500mg tablets at a time.
Do not take paracetamol with other medicines containing paracetamol.
Paracetamol is safe to take in pregnancy and while breastfeeding, at recommended doses.
Brand names include Disprol, Hedex, Medinol and Panadol.
3. Who can and cannot take paracetamol
Most people can take paracetamol safely, including pregnant and breastfeeding women.
However, some people need to take extra care with paracetamol.
Check with your doctor or pharmacist if you:
have had an allergic reaction to paracetamol or any other medicines in the past
have liver or kidney problems
regularly drink more than the maximum recommended amount of alcohol (14 units a week)
take medicine for epilepsy
take medicine for tuberculosis (TB)
take the blood-thinner warfarin and you may need to take paracetamol on a regular basis
4. How and when to take it
Paracetamol can be taken with or without food.
The usual dose for adults is one or two 500mg tablets up to 4 times in 24 hours.
Always leave at least 4 hours between doses.
Overdosing on paracetamol can cause serious side effects. Do not be tempted to increase the dose or to take a double dose if your pain is very bad.
Different types of paracetamol
Paracetamol is widely available as tablets and capsules.
For people who find it difficult to swallow tablets or capsules, paracetamol is also available as a syrup or as soluble tablets that dissolve in water to make a drink.
5. What if I forget to take it?
If you take paracetamol regularly and miss a dose, take it as soon as you remember. However, skip the missed dose if it's nearly time for your next dose.
Never take double doses of paracetamol. Do not take an extra dose to make up for a missed one.
If you forget doses often, it may help to set an alarm to remind you. You could also ask your pharmacist for advice on other ways to help you remember to take your medicine.
Surfactant componentsIn relation to the cleansing enterprise, surfactants are the maximum versatile components used to create optimized cleansing formulations.
Surfactants lessen the surface tension between liquids and the interfacial anxiety between a liquid and a solid.
This reduction ends in a boom in spreading and wetting capability, giving a good deal higher cleaning outcomes.Surfactants are most generally used as wetting agents inside the form of soaps and detergents for cleaning oil and dirt from a floor, however are also utilized in insolubilizing, dispersing, and foaming programs.How Do Surfactant components paintings?Surfactants are amphiphilic, meaning they've each hydrophobicity (water-repelling) and hydrophilic (soluble in water) residences.
Surfactants also can lower the surface anxiety of agricultural remedies in order that nutrients may be greater conveniently absorbed by the plant.Anionic and Nonionic Surfactant additivesThere are quite a few specific surfactant additives that might be applied for numerous motives.
it can, however, purpose skin irritations.Nonionic surfactants, which include Aqua-Cleen®, don't have any charge and are frequently discovered in food, laundry, dishwasher detergents as well as in degreasers and plenty of difficult surfaces cleaning applications.
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CAS No:132684-60-7Formula:C21H23NO4Synonyms:FMOC-L-TLE-OH;FMOC-L-T-BUTYLGLYCINE;FMOC-L-TERT-LEUCINE;FMOC-TLE-OH;FMOC-TBU-GLYCINE;FMOC-TBU-GLY-OH;FMOC-ALPHA-T-BUTYL-GLY-OH;FMOC-ALPHA-T-BUTYLGLYCINEChina Export:From 2018.11 to 2019.11, total export volume of Fmoc-L-tert-leucine from China was 76,865,630KG while total export value was $825,816,556.
The biggest proportion of exporting volume in the last 12 months was 14.24% in 2019.05.Chemical Products Fmoc-L-tert-leucine DescriptionsolidChemical Products Fmoc-L-tert-leucine Basic AttributesCAS No：132684-60-7Molecular Formula ：C21H23NO4Molecular Mass ：353.41Exact Mass ：353.162720PSA ：75.6 A^2LogP ：4.4InChIKeys ：VZOHGJIGTNUNNC-GOSISDBHSA-NH-bond Acceptor ：4H-bond Donor ：2SP3 ：0.33RBN ：6Chemical Products Fmoc-L-tert-leucine CharacteristicsDensity ：1.209±0.06 g/cm3(Predicted)Melting Point ：124-127 °CBolling Point ：554.1±33.0 °C(Predicted)Flash Point ：288.9±25.4 °CRefractive Index ：1.584Storage Condition ：2-8°CChemical Products Fmoc-L-tert-leucine Safety InformationHazard Class ：IRRITANTHS Code ：29242990UN No.
：NONH for all modes of transportWGK_Germany ：3Safety Instructions ：22-24/25P Code ：P261, P264, P271, P280, P302+P352, P304+P340, P312, P321, P332+P313, P362, P403+P233, P405, P501Hazard Statements ：H315Chemical Products Fmoc-L-tert-leucine Production MethodsTake 500mL of the reaction bottle, Chiral amino acids S-3b (5.1 g, 38.6 mmol) were added to the reaction flask, respectively, Dioxane (40 mL) and10percent sodium carbonate (100 mL), The reaction flask was placed in an ice bath, mechanically stirred, To the dropping funnel was added l-chloroformate-9-fluorenylmethyl ester (10.0 g, 38.6 mmol) andDioxane (100 mL), Slowly drop into the reaction flask and gradually return to room temperature and stir overnight.After completion of the reaction, add water 100mL, extracted with 50mL ether three times, take the water phase into the ice bath to cool, add 1M dilute HCl to PH 1.The aqueous solution was extracted three times with 50 mL of ethyl acetate.The oil phase was combined and dried over magnesium sulfate and filtered to dryness to give intermediate S-4b (14.3 g, 96percent).
In the reaction, the raw materials called reactants interact with each other.
After a high-energy transition state (reaching the activation energy of the reaction), the chemical bonds between the reactants break and rearrange to produce one or more chemical products.Products in chemical equations When the chemical equation is written, the reactants are listed on the left, followed by the reaction arrow, the final by-products.
A plus B goes to C plus DWhere A and B are the reactants, and C and D are the products.In a chemical reaction, atoms rearrange themselves, but they are not created or destroyed.
During a chemical reaction, the reactants are converted to products after a high-energy transition state.
This process results in the depletion of the reactants.
It can be a spontaneous reaction, a catalyst that reduces the energy of the transition state, or a medium that provides a solvent for the chemical environment necessary for the reaction to take place.
