Atopic illnesses, such as asthma, rhinitis, and eczema, are common among Vernal Keratoconjunctivitis patients’ families or medical histories. However, in 42–47 percent of patients, VKC is not linked with a positive skin test or RAST, indicating that it is not entirely an IgE-mediated condition. A Th2-driven process involving mast cells, eosinophils, and lymphocytes has been proposed.
“When you encounter a child with a severe type of vernal keratoconjunctivitis, you immediately sense the lack of knowledge of its pathophysiology that stops you from appropriately treating the signs and symptoms that will most certainly damage his childhood,” it has been claimed. 1 The term “morning misery” refers to the pain, blepharospasm, and mucous discharge that these individuals frequently experience when they first wake up.
The clinical management of VKC necessitates a prompt diagnosis, appropriate treatment, and prognosis assessment. The diagnosis is usually made based on the disease’s signs and symptoms, although in certain cases, conjunctival scraping, which shows the presence of infiltrating eosinophils, can help. There are several therapeutic alternatives available, the most of which are topical, and should be chosen based on the severity of the condition. To avoid secondary glaucoma, the most effective medications, steroids, should be used with caution and only for short periods of time.
