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Moximed reports data from MISHA Knee System study

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Theo West
Moximed reports data from MISHA Knee System study

Data from the crucial Calypso Study of Moximed's MISHA Knee System have been released.

The MISHA Knee System, an implanted shock absorber (ISA), is intended to treat osteoarthritis market of the knee.


Its goals are to reduce discomfort, preserve function, and offer a therapy alternative that can postpone arthroplasty.


The objective of the 81-participant multicenter, prospective clinical trial was to evaluate the efficacy and safety of the MISHA Knee System in comparison to high tibial osteotomy (HTO) for the treatment of symptomatic osteoarthritis.


The MISHA Knee System demonstrated lower pain scores and increased function scores for trial participants, proving the superiority of its primary aim. "In our investigational device exemption (IDE) trial, the MISHA Knee System was compared to the high standard set by high tibial osteotomy, a well-known orthopedic operation," stated Anton Clifford, CEO of Moximed.



"A fantastic conclusion for patients is to demonstrate superiority against an established method, with proven results. "The device was found to be superior than high tibial osteotomy (HTO) at two years, according to the manufacturer, who also stated that the system met its primary goal.


The MISHA Knee System demonstrated a composite success rate of 85.6% in the Calypso Study, as opposed to HTO's 65.5%.


Additionally, it demonstrated superiority on all of the study's secondary endpoints, such as improvement in the Western Ontario and McMaster Universities Arthritis Index (WOMAC)-derived Knee Injury and Osteoarthritis Outcome Score (KOOS) pain and function ratings at three and 24 months, as well as time to finish weight bearing.


With each step you take while walking, the MISHA implant, which is attached to the medial knee, reduces peak stresses on the knee by more than 30%.


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