The Global Phosphoramidite Market is associated with synthesis of DNA and RNA oligonucleotides which find applications in DNA sequencing, diagnostics and analysis of genetic variations. Phosphoramidite monomers are used in solid phase oligonucleotide synthesis which allows high throughput commercial production of customized DNA and RNA fragments. The oligonucleotides synthesized from phosphoramidites are used in various genetic sequencing technologies like Sanger sequencing, next generation sequencing and third generation sequencing. The rising investments and advances in DNA sequencing is a key growth driver for the demand of phosphoramidite monomers.
The Global Phosphoramidite Market is estimated to be valued at US$ 1,011.3 MN in 2024 and is expected to exhibit a CAGR of 7.3% over the forecast period 2024 to 2031.
Key Takeaways
Key players operating in the Global Phosphoramidite Market are Glen Research, ChemGenes Corporation, Link Technologies Ltd., BioAutomation Corporation, Merck KGaA, Sigma-Aldrich (now part of MilliporeSigma, a Merck Group company), LGC Biosearch Technologies, Thermo Fisher Scientific, Biosynthesis Inc., ATDBio Ltd., Genscript Biotech Corporation, Expedeon AG, Wuxi Donglin Sci & Tech Development Co., Ltd., Bio-Synthesis Inc., and ChemGenes Corporation.
The demand for phosphoramidite monomers is growing owing to the increasing applications of DNA sequencing technologies in the fields of genetic research, diagnostics, forensic analysis and monitoring genetic variations related to diseases. As per estimates, Global Phosphoramidite Market Size is expected to reach over US$ 60 Billion by 2026.
The major phosphoramidite producers are focusing on expanding their geographic footprint by strengthening their distribution networks across Americas, Europe, Asia Pacific and rest of world regions where robust growth is witnessed in genetic analysis research and laboratories. Regional production facilities are also being set up by key players to ensure security of supply and timely delivery.
Market drivers
The key driver for the Global Phosphoramidite Market is the continued advancements and declining costs of DNA sequencing technologies. Next generation sequencing methods have revolutionized genetic analysis by allowing unprecedented scale of DNA sequencing. Huge genomic data generation is fueling the demand for phosphoramidite based oligonucleotides. Growing application areas of DNA sequencing such as whole genome sequencing of bacteria, plants and human genomes, metagenomics, transcriptomics and epigenetics are propelling the need for phosphoramidite building blocks.
The global Phosphoramidite Market is facing impact due to geopolitical conflicts and economic uncertainties in various regions. The ongoing Russia-Ukraine war has disrupted the supply chains and exports of key raw materials from these countries. Russia and Ukraine have significant presence in production and exports of commodities like ammonia, fertilizers and gases which are important inputs for manufacturing phosphoramidites. Prolonged war and sanctions have led to unpredictable price fluctuations and non-availability of these resources impacting the production capacity and costs of phosphoramidite producers globally. Similarly, deteriorating relations between US and China and potential trade restrictions can adversely affect the established supply networks between manufacturers based in these countries.
The pandemic recovery is also slowing down in major markets like Europe and China due to rising inflationary pressures. Such economic slowdowns would lower research spending and demand for phosphoramidites in pharmaceutical and biotechnology sectors in the short term. To counter current geopolitical challenges, phosphoramidite manufacturers will need to diversify their sourcing networks, explore new supply partnerships and look for alternative raw material options. They also need to focus on expanding their customer base in other fast growing countries and markets to mitigate risks of overdependence on select major economies.
The North American region currently holds the largest market share in terms of value for global Phosphoramidite Market. Within North America, the United States dominates the regional market and accounts for the highest consumption. This is because of strong presence of leading R&D driven pharmaceutical and biotech companies requiring phosphoramidites for DNA synthesis applications. The Asia Pacific region is expected to be the fastest growing market during the forecast period. Rapid development of domestic biomedical industries, growing government investments in healthcare infrastructure and rise of India and China as global life science hubs are driving the demand for phosphoramidites in Asia Pacific region.
The Asia Pacific region holds huge growth potential and is expected to be the fastest growing regional market for phosphoramidites during the forecast period. Rapid economic development, growing healthcare expenditure, increasing stringency of regulatory frameworks and expansion of biomedical sectors are the key factors propelling the demand for phosphoramidites in Asia Pacific. Particularly, China and India stand out as highly lucrative emerging markets. In China, strong government impetus on innovation-driven manufacturing is attracting large investments from global pharmaceutical majors to set up new R&D and production facilities.
This is generating huge requirements for specialized chemicals and reagents like phosphoramidites used in DNA sequencing, genomic research and new drug development. India is also emerging as an important life science hub with presence of quality research institutes, low-cost skilled workforce and favorable FDI policies. Leading global vendors are actively partnering with or acquiring production units in Asia to serve the regional as well as international customers from this strategic location, giving additional boost to the market. Overall, the Asia Pacific Phosphoramidite Market is estimated to exhibit healthy double digit CAGR during the forecast period due to rapidly expanding biomedical industry and research expenditures across the region.
Get More Insights on Phosphoramidite Market
Oligonucleotides readily bind in specific sequencing manner to their respective DNA-RNA oligonucleotide to form duplex chain.
Oligonucleotides are chemically synthesized molecular chains with phosphoramidite components of natural or chemically modified nucleosides and have wide range of applications in generic testing, research, and forensic.The global oligonucleotide synthesis market is estimated to be valued at US$ 2,874.1 Million in 2020 and is expected to exhibit a CAGR of 11.3% during the forecast period (2020-2027).Request Sample Copy of Research Report @ https://www.coherentmarketinsights.com/insight/request-sample/4257Increasing research and development activities in the field of genomics and genetics is expected to propel the market growth during the forecast periodResearch institutes and diagnostic centers have shifted their focus on genomics and genetics due, which has increased demand for high quality synthesized oligonucleotides in the market over the past few years.
For instance, in July 2020, researchers of Rosalind Franklin University of Medicine and Science initiated a new therapeutic approach for treating Batten disease, a fatal neurodegenerative disease in children with the help of antisense oligonucleotides.
These factors are expected to drive the global oligonucleotide synthesis market growth over the forecast period.Expansion of manufacturing facilities by market players is expected to drive the market growth during the forecast periodBiotechnological companies are focusing on expanding their manufacturing facilities due to increasing demand for oligonucleotides from pharmaceutical companies.
For instance, in March 2020, STA pharmaceuticals, a subsidiary of WuXi AppTech, announced inauguration of its large scale oligonucleotide active pharmaceutical ingredient manufacturing facility in China.Global Oligonucleotide Synthesis Market – Impact of Coronavirus (COVID-19) PandemicThe coronavirus disease (COVID-19) outbreak was first reported on December 31, 2019, in Wuhan, China.
The World Health Organization declared COVID-19 as pandemic on March 11, 2020.According to the Coronavirus Disease (COVID-19) Weekly Epidemiological Update by the World Health Organization, over 61.8 million cases and 1.4 million deaths due to coronavirus disease (COVID-19) were reported up till November 29, 2020 across the globe.In order to deal with the COVID-19 pandemic, market players and government authorities are collaborating, in order to explore the oligonucleotide platform for the development of COVID-19 treatment.
The Spirulina Market is expected to grow at a CAGR of 10.3% from 2020-2030, according to a new research report by Next Move Strategy ConsultingSpirulina is a blue green algae with high nutrient content, usually consumed by human & animals.
It is also used as a complementary diet ingredient in aquaculture & poultry feeds owing to the presence of high protein & vitamin content.According to the report, growth in health consciousness among people and the rising demand for dietary supplements are major factors driving the spirulina market growth.
Additionally, high penetration of spirulina in industries such as cosmetics and pharmaceutical owing to the advantageous properties such as anti-aging, anti-wrinkles and othersare bringing changes in market tends.However, low stability & poor sustainability of spirulina derived colours is expected to restrict the market growth.Moreover, growth in research & development activities followed by untapped market opportunities in developing economies are anticipated to provide numerous opportunities to the market players in the coming few years.On the basis of type, spirulina market share is segmented into Arthrospira Platensis and Arthrospira Maxima.
Arthrospira Maxima dominates the global Spirulina market and will be the dominant throughout the forecasted period.On the basis of application, the Spirulina market is categorised into Nutraceuticals, Food & Beverages, Cosmetics, Animal Feed, and Others.Food & Beverages segment is likely to develop significantly over the period of time owing to fast growing food & beverage industry.On the basis of drug formulation, the spirulina market is bifurcated into Powder, Tablet & Capsule, Liquid, and Granule & Gelling Agent.
Powder segment is expected to account for the major market share & dominate the market growth over the forecast period.North America dominates the spirulina market in terms of market size over the forecast period, owing to rising health consciousness among people.
Hansen Holding A/S, Algenol Biofuels Inc., Dongtai City Spirulina Bio-engineering Co., Ltd., Prolgae, Parry Neutraceuticals, Sensient Technologies Corporation, DDW Inc., Algatec and Naturex S.A.Browse key industry insights from the report, “Spirulina Market Size By Type (ArthrospiraPlatensis and Arthrospira Maxima) By Application (Nutraceuticals, Food & Beverages, Cosmetics, Animal Feed, and Others), By Drug Formulation (Powder, Tablet & Capsule, Liquid, and Granule & Gelling Agent)Regional Outlook (U.S., Canada, Germany, UK, France, Spain, Italy, Russia, China, India, Japan, Australia, Indonesia, Malaysia, South Korea, Brazil, Mexico, South Africa, Saudi Arabia, UAE, Kuwait), Growth Potential, Price Trends, Competitive Market Share & Forecast, 2020–2030” in detail along with the table of contents:Key Insights from the Spirulina Market Report:Asia Pacific is the fastest growing region in Spirulina market owing to the rising demand of spirulina from various industries such as cosmetics, food , healthcare and others and government initiatives to promote local spirulina production.The Food & Beverages segment dominates the market in terms of application and is expected to grow at a significant CAGR to maintain the lead till 2030.Some of the major players in the market are DIC Corporation, Cyanotech Corporation, Chr.
