https://medicastemcells.com/does-the-use-of-aspirin-and-nsaids-interrupt-prp-treatment/
There was a time when the physicians used to recommend NSAIDs (Non-Steroidal Anti-Inflammatory Drugs), especially aspirin to reduce the risk of stroke or heart attack. However, the scientists in Montreal confirmed contrarily in 2017 that the current use of NSAIDs significantly increased the risk of a heart attack.1 Therefore, some questions arise. Is the use of NSAIDs a good idea, especially if you are planning a Platelet-rich plasma (PRP) therapy? Do NSAIDs affect the PRP function? Is there any downside? Several research studies report negative results. Let’s dig in.
What is PRP therapy?
Platelet-rich plasma therapy is used to treat varied conditions ranging from orthopaedic ailments to hair loss issues. It has emerged as an effective, promising alternative to surgery. PRP is prepared by concentrating the platelets rich in growth factors in your blood like platelet-derived growth factor (PDGF), transforming growth factor-beta (TGF), vascular endothelial growth factor (VEGF), epidermal growth factor (EGF), fibroblast growth factor (FGF), and connective tissue growth factors. Once the physician injects these concentrated platelets into the damaged tissues, they slowly release the growth factors to promote natural healing. However, what you take as far as daily medications may impact the efficacy and natural healing of the PRP.
What are NSAIDs and Aspirin?
NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) are a class of standard household medication used worldwide to reduce pain and inflammation. These can also reduce fever, hence, are recommended for short- and long-term diseases/conditions such as flu, arthritis, back pains, dental pains and other conditions. NSAIDs are available as over the counter medication and prescription. Among the NSAIDs, aspirin is the most well-known drug across the world. It has been widely used since just before the 20th century (1899). Aspirin alone stands out due to its increased blood-thinning ability. Hence, aspirin can effectively prevent blood clot formation.
So is NSAIDs and aspirin use a good idea? Some studies suggest probably not if you are planning a PRP treatment. Let’s review.
What is the role of NSAIDs in PRP treatment?
Even though NSAIDs are effective pain relievers, they hinder platelet activation and aggregation by inhibiting cyclooxygenase (COX) enzymes. This inhibition will consequently prolong the bleeding time and platelets will not be able to secrete the growth factors.2 Due to this impaired platelet function, patients consuming NSAIDs will not have any therapeutic effect when undergoing PRP treatment.
However, there is a difference between the effects of aspirin and non-aspirin NSAIDs upon the platelets. Aspirin irreversibly inhibits cyclooxygenase enzymes; therefore, its actions stay for the lifespan of the circulating platelets (about 8–10 days). Where non-aspirin NSAIDs reversibly block cyclooxygenase enzymes and, hence, the extent of their action depends on the relevant drug dose, half-life and serum level.3By discontinuing the consumption of NSAIDs, especially Naproxen for a minimum of one week before PRP treatment,it may improve the secretion of biological factors.4
So what does it mean if you are taking NSAIDs and are planning to undergo a PRP treatment? It means your NSAIDs use, especially aspirin, could sabotage your PRP treatment leading to less desirable outcomes than what they could be.
How long the effects of NSAIDs last?
When should you stop NSAIDs and especially aspirin prior to a PRP procedure? It takes around ten days for the effect of NSAIDs and aspirin to wear off. Hence, to be on the safe side, you should stop the NSAIDs two weeks prior to the PRP therapy. Similarly, as the injected platelets release growth factors for around two weeks, you should stay off the NSAIDs after the PRP procedure also. However, always discuss with your doctor before stopping any medication!
So what's the upshot?
Considering the effect of NSAIDs in PRP therapy, it is best to discontinue NSAIDs two weeks before and after the PRP procedure to get the best possible outcomes of the procedure. Just follow the guidelines above after a careful discussion with your doctor.
There are people who suffer from severe hair fall for reasons that might be genetic or other health related issues.
Hair loss or thinning of hair is a common problem faced by both men and women which can also occur due to ageing or stress.While looking for a solution, one might come across several solutions but choosing the right one is what makes a difference.
There are some solutions which are proven to be significantly better at curing the problem than others.One such solution is known as PRP.What is PRP?Platelet-rich-plasma is a process in which a substance is taken from your blood and then injected into your scalp which further helps to cure a lot of problems such as follicles (where your hair grow from) and helps heal other bodily tissues.It is a process which increases the concentration of certain proteins that contribute towards healing in your body.Not just hair loss, but a number of health problems can be treated with the help of PRP such as tendon injuries and osteoarthritis.
As per studies, it is a proven scientific method to treat baldness in men, also known as androgenic alopecia.How effective is PRP for hair fall?We, at Vardaan Clinic aim to give the best results to our patients and believe in giving the right advice.Being an in-office, non-surgical treatment, PRP can be performed within 30 minutes.
PRP is more effective on patients with “weak quality” of hair growth on their scalp as opposed to those having shiny bald spot.According to research, the best candidate is the person who has recently started to experience loss of hair.
PRP isn’t advisable for people who are completely bald.It can be particularly effective in female pattern hair loss.Duration of the treatmentThe full procedure takes nearly 30 minutes to complete.
The global platelet rich plasma market is slated to touch a value of nearly US$ 391 Mn in the year 2022 and grow at a robust CAGR during the assessment period.
As per the forecast of Fact.MR, the pure platelet-rich plasma kits segment is slated to touch a value of nearly US$ 90 Mn in the year 2022.
The pure platelet-rich plasma kits segment is estimated to account for more than one-fourth of the revenue share of the product type segment by the year 2017 end and is expected to lose market share by the year 2022-end.Read Report Summary: https://www.factmr.com/report/170/platelet-rich-plasma-marketAs per the forecast of Fact.MR, the dermatology clinics segment will reach a value of nearly US$ 58 Mn in the year 2017.
Platelet-rich plasma has got many applications in the healthcare industry, especially in areas such as orthopedic surgeries, treatment of sports injuries and treatment of neurological diseases, amongst others.
Besides these applications, the platelet-rich plasma therapy is also finding new applications in treatment of medical conditions such as erectile dysfunction, and in the facelift surgeries.Request for Report Methodology: https://www.factmr.com/connectus/sample?flag=RM_id=170As platelet-rich plasma is derived from blood plasma along with several other growth factors, it facilitates a quick healing of bone tissues and other soft tissues.
However, the high costs involved in the platelet-rich plasma therapy may restrain the growth of this market during the forecast period.
Omniya Clinic offers a variety of rejuvenating treatments for internal and external health like Platelet Rich Plasma Therapy or Vampire facial.Call 020 7584 4777.
For more information please visit: https://www.omniya.co.uk/blog/your-guide-to-platelet-rich-plasma-therapy-prp/
