Gabapentin was initially effective due to its effects on the GABA neurotransmitter and provided tranquility and sleep. Now it is thought that the activity is due to the fact that it is a calcium channel blocker. It could reduce the secretion of certain neurotransmitters that cause pain and stimulate the brain. According to several reports, many ME patients were given more energy by Gabapentin. Unfortunately, the effects seem to gradually decline in many people.
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