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23b-PVP / Buy 23B-PVP Online23b-PVP / Buy 23B-PVP Online.α-Pyrrolidinopentiophenone (also known as α-pyrrolidinovalerophenone, α-PVP, O-2387, β-keto-prolintane, prolintanone, or desmethylpyrovalerone) is a synthetic stimulant of the cathinone class developed in the 1960s[1] that has been sold as a designer drug.
[note 1] α-PVP is chemically related to pyrovalerone and is the ketone analog of prolintane.Adverse effects Of 23b-PVP / Buy 23B-PVP Online23b-PVP / Buy 23B-PVP Online .α-PVP, like other psychostimulants, can cause hyperstimulation, paranoia, and hallucinations.
α-PVP has been reported to be the cause, or a significant contributory cause of death in suicides and overdoses caused by combinations of drugs.α-PVP has also been linked to at least one death with pulmonary edema and moderately advanced atherosclerotic coronary disease when it was combined with pentedrone.According to Craig Crespi in the journal Case Reports in Psychiatry, ‘symptoms are known to easily escalate into frightening delusions, paranoid psychosis, extreme agitation, and a multitude of other altered mental states.’ Common adverse effects of α-PVP are in line with other psychostimulants, and include:23b-PVP / Buy 23B-PVP OnlineDelusionsParanoid psychosisAgitationAltered mental stateIn addition, agitated delirium may occur as an adverse effect of α-PVP,[12] which carries its own set of symptoms, including anxiety, agitation, violent outbursts, confusion, myoclonus and convulsions, with clinical symptoms including tachycardia, hypertension, diaphoresis, mydriasis and hyperthermia.Pharmacologyα-PVP acts as a norepinephrine-dopamine reuptake inhibitor with IC50 values of 14.2 and 12.8 nM, respectively, similar to its methylenedioxy derivative MDPV.
[20]Detection in body fluidsα-PVP may be quantified in blood, plasma or urine by liquid chromatography-mass spectrometry to confirm a diagnosis of poisoning in hospitalized patients or to provide evidence in a medicolegal death investigation.
On January 28, 2014, the U.S. DEA listed it, along with nine other synthetic cathinones, on the Schedule 1 with a temporary ban, effective February 27, 2014.
[24]As of October 2015, α-PVP is a controlled substance in China.
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