The first COVID-19 Vaccines approved by WHO is Pfizer-BioNtech vaccine or Comirnaty. A COVID19 vaccine is designed to confer acquired immunity against the coronavirus which induces severe acute respiratory syndrome type 2 (SARSCoV2).
Coronavirus disease 2019 (COVID-19) is a contagious infection caused by coronavirus 2 that leads severe acute respiratory syndrome (SARS-CoV-2). The first case of Covid-19 discovered in Wuhan, China, in Dec. 2019. Since then, the disease has spread over the world, resulting in a pandemic.
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1. Pfizer–BioNTech – BNT162b2
This COVID-19 vaccine, sold under the trade name Comirnaty. It is also an mRNA-based COVID-19 vaccine developed by BioNTech, a German biotechnology company, in union with Pfizer, an American pharmaceutical company, for clinical trials, logistics, and producing assistance. In addition, the vaccine works well intramuscularly. But the time increased to 42 days in the United States and four months in Canada. Comirnaty COVID-19 Vaccines approved by WHO (World Health Organization) on 31st December 2020 for emergency use.
2. Oxford–AstraZeneca – AZD1222
t is a main viral vector vaccine. In addition, it sells its products under the brand names Vaxzevria and Covishield. Oxford University and British-Swedish corporation AstraZeneca in the UK tested on the Chimpanzee as a vector. However, the vaccine works in deltoid muscle.
3. Serum Institute of India- AZD1222 (Same formulation of Oxford and AstraZeneca-AZD1222 )
Serum Institute of India made the Covidsheid vaccine. Covishield is an Indian version of the Oxford-AstraZeneca covid vaccine manufactured in India. Serum Institute’s Covishield COVID-19 Vaccines Approved by WHO (World Health Authorization) on Feb. 15, 2021. Later on, Mar. 19 2021, WHO confirmed that Covishield had a positive benefit-risk profile. Moreover, it also shows a strong ability to prevent infections and reduce death rates worldwide.
4. Janssen or Johnson & Johnson – Ad26.COV2.S
The COVID-19 vaccine is also known as the Johnson & Johnson COVID-19 vaccine. Janssen COVID-19 vaccine produced by Janssen Vaccines in Leiden, Netherlands, and its Belgian parent firm Janssen Pharmaceuticals, a Johnson & Johnson affiliate.
This is a human adenovirus-based vaccine that has been genetically modified to contain the SARS-CoV-2 virus’s spike protein which develops COVID-19 infection. The vaccine solely needs one service and does not require refrigeration. The vaccine is 66% effective in preventing COVID-19 in a one-dose regimen. It is 85 % effective in avoiding severe COVID-19, and 100% successful in preventing the illness. Janssen COVID-19 Vaccines approved by WHO (World Health Organization) on 12th March 2021 for emergency use.
5. Moderna – mRNA-1273
The Moderna COVID-19 vaccine is also known as mRNA-1273. Moderna covid19 vaccine developed by Moderna, the National Institute of Allergy and Infectious Diseases (NIAID), the Development Authority in the United States, and Biomedical Advanced Research is marketed under the trade name Spike Vax. It is an R.N.A. vaccine made up of lipid nanoparticles encased in nucleoside-modified mRNA (modRNA) expressing a SARS-CoV-2 spike protein. About two weeks following the first dosage of Spikevax, evidence of vaccination effectiveness emerges. Covid19 can be prevented by immunization in two weeks after the second vaccine dosage. Effectiveness was measured at 94.1 %. Vials of Spike Vax could be stored in freezers, making distribution more accessible, particularly in developing nations.
6. Sinopharm – BBIBP-CorV (Vero Cells)
Sinopharm BIBP-CorV is a type of inactivated virus COVID-19 vaccine. BIBP-CorV was established by Sinopharm’s Beijing Institute of Biological Products. Sinopharm BIBP, or BIBP-CorV, is produced in China. Moreover, it depends on the same technology as CoronaVac and Covaxin.
The vaccine works nicely at deltoid muscle. In addition, there are two dosages in the first course. Moreover, the WHO suggests a three to the four-week gap between doses. It also offers 78.1% efficiency against illness. 100% effective against severe cases in Phase III studies in the United Arab Emirates and Bahrain, according to data circulated in JAMA. However, the U.A.E. recently recorded average data showing 86% efficiency in December 2020.
7. Sinovac – CoronaVac
Sinovac Biotech in China made this Covid-19 vaccine. In contrast with other coronavirus vaccines, Coronvac uses standard technology.
This vaccine does not require storing and placing at low temperature. Therefore, both the complete product and the raw material of the vaccine will transport at 2–8 °C (36–46 °F).
It is 66% effective against symptomatic cases of SARS-CoV-2, in severe cases 88% effective, 90% effective against I.C.U., and 86% effective against mortality in a real-world study of tens of millions of patients who got it.
8. Bharat Biotech – BBV152 A,B,C
It collaborates with the Indian Council of Medical Research – National Institute of VirologyC to develop Covaxin (BBV152). This is a COVID-19 vaccine. In a study of 130 real cases, it showed 77.8% efficiency against COVID-19 illness, with 24 cases in the vaccine group against 106 in the placebo group.
The Covaxin was the first made in India vaccine developed for SARS-CoV-2 infections. As per the study, The vaccine was 93.4% effective against severe COVID-19 illness. The effectiveness studies show that it protects against COVID-19 by 63.6%. It’s a vaccine that doesn’t need freezer storage, doesn’t require reconstitution. It comes in liquid form in multi-dose vials that’s stable at 2-8 degrees Celsius. Covaxin COVID-19 Vaccines approved by WHO (World Health Organization) on 3rd November 2021 for emergency use.
9. Novavax – NVX-CoV2373
Novavax and the Coalition for Epidemic Preparedness Innovations (CEPI) made this vaccine. Moreover, the brand names of this vaccine are Nuvaxovid and Covovax.
It has two doses and is stable at low temperatures of 2 to 8 °C (36 to 46 °F). In addition, the most common side effects are headaches, feeling ill or vomiting, muscle and joint pain, warmth and pain at the injection site, fatigue, and feeling unwell.
In December 2021, the vaccine fulfilled its primary aim of preventing infection for at least seven days following the second dose in a phase 3 trial. Moreover, the vaccine offers all-around efficiency of 90.4%, with 100% efficiency against illness. Covavax COVID-19 Vaccines approved by WHO (World Health Organization) on 17th December 2021 for emergency use.
10. Serum Institute of India – NVX-CoV2373 (Same formulation of Novavax -NVX-CoV2373 )
It is an Indian version of the Novavax covid vaccine. In September 2020, Novavax also made an agreement with the Serum Institute of India. Moreover, this is an effective vaccine plant that produces up to 2 billion doses per year.
However, this Institute starts the output of the Covovax vaccine under license from Novavax. It is also a part of the COVAX facility portfolio, giving an upgrade to ongoing activities to vaccinate more people in low-income countries.
Conclusion
COVID-19 vaccine are safe and effective in preventing people from becoming seriously ill or dying. In addition to keeping a safe distance from others and avoiding crowds, wearing a well-fitting mask covering your mouth and nose, keeping enclosed rooms well air circulated, cleaning hands regularly, and covering coughs and sneezes, this is one element of managing COVID-19.
Even if you’ve already had COVID-19 infection, take whichever vaccine is made available to you first. It is essential to get vaccine as soon as possible as your chance comes up. Although no vaccination is 100% protective, approved COVID-19 vaccines offer a high level of protection against becoming extremely ill and dying from the disease.
Alexander Johnson Oxford news article.
Learn more about Alexander Johnson here.
The American officials have announced pulling the travel ban from November for fully vaccinated travelers only.
The move come 18-months after a presidential proclamation from Donald Trump closed off the US to British visitors.
Visitors from the UK, Ireland, and the Schengen Area (most of the EU plus Iceland, Norway, Switzerland and Liechtenstein) have been banned from travelling to the US since March 2020.
A presidential proclamation outlawing direct arrivals was made by Donald Trump, who lifted it very briefly at the end of his White House tenure, only for his successor, Joe Biden, to re-impose the prohibition on people who have been physically present in one of those locations during the 14-day period preceding their entry or attempted entry into the United States Read more....
The House of Brazil has a new challenge to face - allegations of corruption over vaccine purchase.Two testimonies in front of a Parliamentary Commission rocked the country recently after the witnesses - officials in the Health Ministry - revealed how they were pressured to sanction overpriced Covaxin orders by the government.The Brazilian President has been infamous for taking COVID-19 dangers lightly and advocating unproven drugs like HCQ.
Aides close to him are now alleged to have railroaded govt functionaries to buy vaccines at jacked up prices from Bharat Biotech.Click on the link below to read more details and to find out what the Indian company has said in its involvement in the matter.https://transfin.in/all-there-is-to-know-about-the-brazil-covaxin-scandal
To be fit is the choice of millions of people, and going to the gym is a norm for many.
There are a lot of investments in personal trainer apps at the moment, and the market is continuously growing.
Today, we’ll consider one of the most popular apps that is named in nearly all the best fitness apps rankings – Official 7 Minute Workout by Johnson & Johnson.
To train with a 7 Minute Workout application, you don’t need to have any professional equipment: only your body weight, a wall, and a chair.
Users have access to 72 different exercises and 22 additional workouts that differ in complexity and duration so they can find a suitable program at any level of training.
With this framework, your app will be able to play video and audio files from raw resources and standalone files in the filesystem or over the network.
With COVAXIN by Bharat Biotech getting the regulatory nod for human trials along with another India candidate, interest on vaccine again returned in public discussion.
