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Antimicrobial Silver-Ion Technology: The Silver Bullet For Infections

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Antimicrobial Silver-Ion Technology: The Silver Bullet For Infections

Catheter-related Blood Stream Infection (CRBSI) have become a major challenge for hospitals worldwide. HAIs are the leading causes of hospital-acquired conditions and patient deaths. This article provides an overview of antimicrobial silver-ion technology and its potential role in preventing infections.


Historically, silver ions (Ag-ions) have been used in burns and wound treatments; and food and water preservation by Greeks, Romans, and Egyptians for their antimicrobial properties. The silver atom transforms into a silver cation (Ag+) when it loses one or more electrons and attains a highly reactive state. The Ag+ easily binds to the tissue proteins of microbes, causing vital structural changes that help prevent infections.

Ag-ion antimicrobial technology is a highly versatile, patented, and innovative technology of incorporating silver ions into coatings, textiles, and polymers in a multitude of applications for controlling infections by checking colonisations, and providing sterilization against most microbes including bacteria, fungi, and viruses.

Ag-ion technology works against 150 strains of bacteria, both gram-positive and gram-negative like S.aureus, MRSA, S.epidermidis, P.aeruginosa, E.coli, K.pheumoniae, and fungi like C.albicans, and yeast.[2] Recent studies have even brought to light the antimicrobial efficacy of Ag-ion against certain viruses, like Coronavirus. (tested and published by sciessent, Feb 10, 2020).


How do silver ions attack microbes?

The silver ions have oxidizing properties, and because they are positively charged, they readily attract negatively charged microbe cells. There are three main mechanisms by which these ions can attack the microbes:

  1. Ag+ ions react with the peptidoglycan component of microbes’ cell wall and eat away at it, creating pores (lysis).
  2. Ag+ ions penetrate the bacterial cell wall and block cellular respiration, hence disrupting the metabolism of the microbe.
  3. Ag+ ions cause damage to the DNA of the microbe and its replication process. For more information: https://vygonindia.com


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