Organ on a chip is a microfluidic cell culture device which aims to replicate human physiology and pathology. It helps to study tissue and organ level interactions in a controlled environment which is useful in drug development and toxicity testing.
Market Dynamics:
Technological advancements in developing organs on chip is a major driverfueling growth of the market. For instance, researchers at the University of California, San Diego developed an artificial small intestine using microengineering whichaims to replicate key aspects of small intestinal tissue physiology. It consists of human intestinal epithelial cells cultured in microfluidic channels lined by porous membranes. The device closely mimics the tissue-tissue interfaces and peristalsis-like motions of the human small intestine. In addition, rising adoption of organ on a chip technology by pharmaceutical companies for drug screening and development is also propelling growth of the organ on a chip market. For example, companies likeEmulate and cnBio are using organ chipsto accelerate drug development by replicating human biology and physiology.
Organ On A Chip Market Drivers
Increasing Investment in Drug Discovery and Development". Due to high failure rates and costs involved in clinical trials, many pharmaceutical companies are investing in developing lab grown organ models as an alternative to animal testing. Organ on chip models help identify potential drug toxicity and efficacy at a very early stage thus reducing costs associated with late stage drug failures.
Advancements in Microfluidics and Tissue Engineering". Significant progress has been made in developing microfabrication techniques, 3D cell culture methods and microfluidic organ chip platforms. These advancements allow replication of complex human organ level structures and physiologies on a microchip with integrated functionality. Researchers are better able to mimic human disease conditions and response to drug candidates using these advanced organ chip technologies.
Organ On A Chip Market Restrain
High Development Costs". Designing and fabricating organ chip microchips requires extensive multidisciplinary expertise. Obtaining primary human cells, developing multi-layer microfluidic organ structures and integrating various organ functionalities on a single microfluidic chip is a complex process which demands significant initial investments. This acts as a restraint for small companies and startups to enter this market.
Organ On A Chip Market Opportunity
Personalized Medicine". Organ chips allow development of patient-specific disease models using cells obtained from individual patients. These personalized organ chip models can be used to identify most effective therapies tailored to a patient's unique genetic profile. This presents a major opportunity for organ chip technologies to transform drug discovery and development towards a more personalized medicine approach.
Organ On A Chip Market Trends
Multi-Organ Interaction Models". Current research focus is on developing advanced multi-organ chips where different organ chips can be linked to mimic inter-organ communication within the human body. These multi-organ chips will provide a more holistic understanding of how drugs or disease conditions may affect the complex interactions between different organs and systems in the body. This reflects the growing market trend towards developingdisease models with greater complexity and physiological relevance.
Organ-on-a-chip Market Research Report: By Organ Type (Lung-on-Chip, Heart-on-Chip, Liver-on-Chip, Intestine-on-Chip, Kidney-on-Chip, Human-on-Chip), By Application (Drug Discovery, Toxicology Research, Others) and By End-User (Pharmaceutical Companies, Research Organizations, Others) – Forecast to 2027Overview:The global organ-on-a-chip market is expecting a strong CAGR for the coming years during the forecast period covering 2019 to 2025.
A surge in the creation of better human disease models can also boost the prospect of this market.
The fetched data from these segments are expected to help the assessment of various strategic moves of this market.
By organ type, the global market can be segmented on the basis of lung-on-chip, heart-on-chip, intestine-on-chip, liver-on-chip, kidney-on-chip, human-on-chip, skin-on-chip, and blood-brain barrier-on-chip.
Other segments are also in line to impact the global healthcare sector.
North America is known for its superior infrastructure and benefits related to funding, owing to which the market may record easy growth in the coming years.
Market HighlightsAccording to MRFR analysis, Organ-On-a-Chip Market is expected to register a CAGR of 53% during the forecast period of 2019 to 2025 and was valued at USD 51.3 Million in 2018.Organs-on-chips (OOCs) are small plastic devices with biocompatible microfluidic chambers, which contain multiple live human cells in a 3D culture that simulate crucial physiological functions of body organs.
These cells are placed in an environment that artificially replicates aspects of the human body, such as morphology, movement, flow, electrical stimuli, and liquid gradients.Request Sample Copy:https://www.marketresearchfuture.com/sample_request/8498The global organ-on-a-chip market is growing owing to various reasons, such as an increase in the number of collaborative sales agreements between pharmaceutical companies and university spin-offs and the availability of advanced models of OOCs in the market.
The Western European market has further been classified as Germany, France, the UK, Italy, Spain, and the rest of Western Europe.
The organ-on-a-chip market in Asia-Pacific has been segmented into Japan, China, India, South Korea, Australia, and the rest of Asia-Pacific.Asia-Pacific is the fastest-growing region in the market.
This is mainly due to the increased application of OOCs for drug screening for the treatment of various chronic diseases and a supportive regulatory framework in Asia-Pacific.
Such favorable factors are expected to boost market growth during the forecast period.The organ-on-a-chip market in the Middle East & Africa has been divided into the Middle East and Africa.SegmentationThe global organ-on-a-chip market has been segmented based on organ type, application, and end-user.The global organ-on-a-chip market has been segregated, based on organ type, into lung-on-chip, heart-on-chip, liver-on-chip, intestine-on-chip, kidney-on-chip, skin-on-chip, blood-brain barrier-on-chip, human-on-chip, and others.The market based on application has been branched into drug discovery, toxicology research, and others.
