Cannabidiol, or CBD, is a lesser-known component of the cannabis sativa plant; its more well-known brother, tetrahydrocannabinol, or THC, is the psychoactive component of marijuana. The plant's origins are said to be in Central Asia, and it was initially used medicinally — or for ceremonies — approximately 750 B.C., though there are various estimations.
THC and cannabidiol are just two of the plant's over 100 cannabinoids. THC is psychoactive, and CBD may or may not be, depending on the research. THC has been shown to enhance anxiety; however, it is unclear whether CBD has the same impact. CBD is being explored to help persons in recovery from THC addiction and cravings.
After three randomized, double-blind, placebo-controlled clinical trials with 516 patients, the Food and Drug Administration authorized Epidiolex, a refined CBD extract, to treat uncommon seizure disorders in patients 2 years and older last year. These trials are the gold standard in medicine, as participants are randomly assigned to one of two groups, with neither the subject nor the investigator knowing whether group is taking the placebo or the treatment.
While there is potential for other illnesses to be treated with the plant extract, Epidiolex remains the only FDA-approved CBD-derived medicine. The majority of cannabidiol research has been conducted on animals, and its present popularity has surpassed science. Ryan Vandrey, an associate professor of psychiatry and behavioral sciences at Johns Hopkins University School of Medicine, said, "We don't have the 101 course on CBD exactly figured out yet."
Is CBD just a fake?
Researchers claim that a few drops of CBD oil in a mocha or smoothie will have no effect. Another factor, according to doctors, could be the placebo effect, which makes patients feel wonderful. When a person believes a drug is working and their symptoms are improving, they are said to be "on the mend."
"CBD is not a sham," said Yasmin Hurd, head of Mount Sinai's Addiction Institute in New York City, who led a double-blind trial of 42 recovered heroin addicts and discovered that CBD reduced cravings and cue-based anxiety, both of which can lead to relapse. "It has potential medicinal value," she says, "but putting it in mascara and tampons, for God's sake, that's a swindle to me."
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